Neural Decoding for Intracortical Brain–Computer Interfaces

Brain-computer interfaces have revolutionized the field of neuroscience by providing a solution for paralyzed patients to control external devices and improve the quality of daily life. To accurately and stably control effectors, it is important for decoders to recognize an individual's motor intention from neural activity either by noninvasive or intracortical neural recording. Intracortical recording is an invasive way of measuring neural electrical activity with high temporal and spatial resolution. Herein, we review recent developments in neural signal decoding methods for intracortical brain-computer interfaces. These methods have achieved good performance in analyzing neural activity and controlling robots and prostheses in nonhuman primates and humans. For more complex paradigms in motor rehabilitation or other clinical applications, there remains more space for further improvements of decoders.