Which Patients Are at Higher Risk for Residual Valves After Posterior Urethral Valve Ablation?

У каких пациентов выше риск сохранения клапанов после аблации задних уретральных клапанов?
Mehdi Shirazi, Mohamadreza Farsiani, Mohammad Natami, K. Izadpanah, Amir Malekahmadi, Abbasali Khakbaz
2014-01-01

posterior urethral valvesrenal parenchymal hyperechogenicityresidual obstructive leafletsvalve ablationvesicoureteral reflux
PURPOSE: To find patients at high risk of obstructive remnant leaflets after valve ablation among boys with posterior urethral valve (PUV), we evaluated any possible relationship between preoperative findings in our patients and residual obstructive leaflets after valve ablation. MATERIALS AND METHODS: We retrospectively reviewed the medical records of 55 patients with PUV that was treated by the same surgeon between 2008 and 2012. Of these, 37 patients (67.3%) had no obstructive remnant leaflets (group A) and 18 patients (32.7%) had obstructive remnant leaflets (group B) in follow-up cystoscopy. Preoperative clinical and radiological findings were evaluated and compared between the groups. RESULTS: AMONG ALL THE PREOPERATIVE DATA WE EXAMINED, THE ANALYSIS REVEALED THAT AGE AT THE TIME OF SURGERY (MEDIAN AGE: group A, 15 months; group B, 7 months; p=0.017), echogenicity of kidneys (p<0.05), presence of vesicoureteral reflux (p<0.05), and grade of reflux (p<0.05) were significantly different between the groups. Method of valve ablation, anterior-posterior diameters of the renal pelvis, renal cortical thickness, bladder wall thickening, and scarring on the dimercaptosuccinic acid scan showed no significant differences between the two groups. CONCLUSIONS: In our patients, younger age at surgery time, hyperechogenicity of renal parenchyma, presence of vesicoureteral reflux, and grade 4 or 5 reflux before surgery had a significant relationship with residual valves. More studies may result in enhanced management of patients at high risk of residual valves after PUV ablation, because the sooner the obstruction is resolved entirely, the better the outcome.
1
Among 55 boys treated for posterior urethral valves, 32.7% had obstructive remnant leaflets on follow-up cystoscopy.
2
High-grade vesicoureteral reflux, specifically grades 4 or 5, was significantly related to residual obstructive leaflets.
3
Renal parenchymal hyperechogenicity and the presence of vesicoureteral reflux were significantly associated with residual valves.
4
Valve ablation method, renal pelvic diameter, renal cortical thickness, bladder wall thickening, and DMSA-scan scarring did not differ significantly between groups.
5
Younger age at surgery was associated with residual obstructive leaflets: median 7 months versus 15 months in patients without remnants (p=0.017).

Boys with posterior urethral valve (PUV) undergoing valve ablation

Preoperative risk factors associated with residual obstructive valve leaflets after PUV ablation, including age at surgery, renal parenchymal echogenicity, and vesicoureteral reflux

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2014-01-01
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Mehdi Shirazi
Mohamadreza Farsiani
Mohammad Natami
K. Izadpanah
Amir Malekahmadi
Abbasali Khakbaz
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