Chinese expert brief consensus on newborn screening of inherited metabolic disorders during the novel coronavirus infection epidemic

Краткий консенсус китайских экспертов по скринингу новорождённых на наследственные метаболические заболевания в период эпидемии новой коронавирусной инфекции
Shan Liu, Dongjuan Wang, Ke-Xing Wan, Hao Liu, Dayong Zhang, Jing Yang, Zhaojian Yuan, Xiaoyan He, Jie Wang, Mingcai Ou, Wenbin Zhu, Yiping Qu, Dehua Zhao, Weipeng Wang, Shiguo Liu, Maosheng Gu, Shuodan Huang, Zhiguo Wang, Lin Zou
2020-04-01

COVID-19 epidemicexpert consensusinherited metabolic disordersneonatal screeningnewborn screening
Novel coronavirus (2019-nCov) infection (COVID-19) rapidly spread across China and 25 countries in the worldwide, which infected not only adults but also children, even neonates. Each year, about 15 million newborns are delivered in China. Newborn screening (NBS) helps effectively prevent some mental retardation, premature death, and adverse outcomes in the early stage of baby, which could detect some inherited metabolic disorders (IMDs). During this COVID-19 epidemic, how to balance the risk of infected 2019-nCov and the risk of disability and teratogenesis of IMDs. Expert members of NBS extra quality assessment in National Clinical Center of Laboratory (NCCL) give a brief consensus for NBS of IMDs in the COVID-2019 epidemic, hoping that the brief consensus could be reference for NBS of IMDs in the other epidemic areas or periods all over the world.
1
It provides expert recommendations for maintaining newborn screening of inherited metabolic disorders during the COVID-19 epidemic in China.
2
The consensus addresses how to balance COVID-19 infection risks against disability, teratogenesis, and premature death risks from undiagnosed inherited metabolic disorders.
3
The consensus emphasizes the preventive value of newborn screening for reducing adverse developmental and health outcomes through early detection of inherited metabolic disorders.
4
The guidance is intended to support newborn-screening practice in other regions or epidemic periods worldwide.

Newborn screening of inherited metabolic disorders during the COVID-19 epidemic

Balancing the risk of 2019-nCoV infection against the risks of disability and teratogenesis from inherited metabolic disorders, including guidance for screening practice

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2020-04-01
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Shan Liu
Dongjuan Wang
Ke-Xing Wan
Hao Liu
Dayong Zhang
Jing Yang
Zhaojian Yuan
Xiaoyan He
Jie Wang
Mingcai Ou
Wenbin Zhu
Yiping Qu
Dehua Zhao
Weipeng Wang
Shiguo Liu
Maosheng Gu
Shuodan Huang
Zhiguo Wang
Lin Zou
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