Chinese expert brief consensus on newborn screening of inherited metabolic disorders during the novel coronavirus infection epidemic
Краткий консенсус китайских экспертов по скринингу новорождённых на наследственные метаболические заболевания в период эпидемии новой коронавирусной инфекции
2020-04-01
SCID: 54.1/2kbfee4a
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COVID-19 epidemicexpert consensusinherited metabolic disordersneonatal screeningnewborn screening
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Abstract (AI)
Novel coronavirus (2019-nCov) infection (COVID-19) rapidly spread across China and 25 countries in the worldwide, which infected not only adults but also children, even neonates. Each year, about 15 million newborns are delivered in China. Newborn screening (NBS) helps effectively prevent some mental retardation, premature death, and adverse outcomes in the early stage of baby, which could detect some inherited metabolic disorders (IMDs). During this COVID-19 epidemic, how to balance the risk of infected 2019-nCov and the risk of disability and teratogenesis of IMDs. Expert members of NBS extra quality assessment in National Clinical Center of Laboratory (NCCL) give a brief consensus for NBS of IMDs in the COVID-2019 epidemic, hoping that the brief consensus could be reference for NBS of IMDs in the other epidemic areas or periods all over the world.
Key Findings
1
It provides expert recommendations for maintaining newborn screening of inherited metabolic disorders during the COVID-19 epidemic in China.
2
The consensus addresses how to balance COVID-19 infection risks against disability, teratogenesis, and premature death risks from undiagnosed inherited metabolic disorders.
3
The consensus emphasizes the preventive value of newborn screening for reducing adverse developmental and health outcomes through early detection of inherited metabolic disorders.
4
The guidance is intended to support newborn-screening practice in other regions or epidemic periods worldwide.
Research Object
Newborn screening of inherited metabolic disorders during the COVID-19 epidemic
Research Subject
Balancing the risk of 2019-nCoV infection against the risks of disability and teratogenesis from inherited metabolic disorders, including guidance for screening practice
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2020-04-01
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