Effectiveness of menthyl acetate synthesis with different acetyl groups equivalent

Эффективность синтеза ментил ацетата с разными эквивалентами ацетильной группы
Sutrisno Sutrisno, Husni Wahyu Wijaya, Rini Retnosari, Daratu Eviana Eka Putri
2021-01-01

acetic acidacetic anhydrideacetyl chloridementhol esterificationmenthyl acetate
One of the factors that determine the effectiveness of an alcohol esterification reaction is the group attached to the acyl chain. The study of the esterification reaction of menthol with acetic acid and its derivatives has been carried out with success. The esterification reaction of menthol was carried out with glacial acetic acid, acetic anhydride, and acetyl chloride. The effectiveness of esterification, both from the yield and the resulting content of menthyl acetate, shows that acetyl chloride is best effective, followed by acetic anhydride and acetic acid in its esterification against menthol.
1
Acetic anhydride showed intermediate effectiveness in menthyl acetate formation compared to acetyl chloride and acetic acid.
2
Acetyl chloride produced the highest effectiveness in menthyl acetate synthesis, measured by yield and product content.
3
Esterification of menthol was performed using glacial acetic acid, acetic anhydride, and acetyl chloride.
4
Glacial acetic acid was the least effective acyl source for menthol esterification to menthyl acetate.

Esterification reaction of menthol with acylating agents (glacial acetic acid, acetic anhydride, acetyl chloride)

Effectiveness of menthyl acetate synthesis measured by yield and menthyl acetate content depending on the type of acetyl (acyl) group/acetylating agent

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2021-01-01
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Sutrisno Sutrisno
Husni Wahyu Wijaya
Rini Retnosari
Daratu Eviana Eka Putri
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