Osteoporosis Update: Personalized Risk Assessment and Treatment

Обновление по остеопорозу: персонализированная оценка риска и лечение
Nayoung Sung, Pelin Batur, Rachel Novik, Madeline Cohn
2026-02-16

osteoporosispostmenopausal women hip fracture inpatient useromosozumab cardiovascular safetytrabecular bone scorezoledronate underuse
The clinical update offers a concise overview of recently published, high-impact journal articles that may influence clinical practice, summarized for our readers. This edition highlights recent studies related to the diagnosis and management of osteoporosis. It reviews essential international guidelines on the clinical use of trabecular bone score (TBS) and a goal-oriented approach to treatment, alongside emerging data on the cardiovascular safety of romosozumab and evidence underscoring the underuse of zoledronate. In particular, it discusses the limited utilization of zoledronate in early postmenopausal women and its inpatient use in older adults after hip fractures.
1
Emerging data assess the cardiovascular safety profile of romosozumab.
2
Evidence indicates zoledronate is underused, particularly in early postmenopausal women.
3
International guidelines on clinical use of trabecular bone score (TBS) and a goal-oriented treatment approach are emphasized.
4
Recent high-impact studies may influence osteoporosis clinical practice by updating diagnosis and management approaches.
5
Zoledronate is often used inpatient for older adults after hip fractures, highlighting differential utilization by setting and age.

Osteoporosis diagnosis and management in clinical practice

Personalized risk assessment and treatment strategies including use of trabecular bone score (TBS), goal-oriented therapy, cardiovascular safety of romosozumab, and utilization patterns of zoledronate

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2026-02-16
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Nayoung Sung
Pelin Batur
Rachel Novik
Madeline Cohn
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