Frontiers in Bioengineering and Biotechnology
Рубежи биоынженерии и биотехнологии
2021-03-02
SCID: 54.1/5dzawj8f
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biomaterialsgrowth factor deliveryregenerative medicinestem cell sciencetissue engineering
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Abstract (AI)
The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs. In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application. Frontiers in Bioengineering and Biotechnology is a member of the Committee on Publication Ethics.
Key Findings
1
Frontiers in Bioengineering and Biotechnology aims to bridge basic scientific discoveries and clinical implementation by providing a multidisciplinary forum.
2
Modern medicine is shifting from symptom suppression and damage repair toward restoring physiological function and regenerating severely damaged tissues and organs.
3
Progress in stem cells, growth-factor delivery, gene transfer, biomaterials, biofabrication, bioreactors, nanotechnology, diagnostics, and imaging enables regenerative therapeutic strategies.
4
Successful clinical translation of biological therapies and devices requires stronger collaboration among scientists, engineers, industry, regulators, and physicians.
Research Object
the translation and clinical application of biological therapies and innovative medical devices
Research Subject
multidisciplinary integration of biomaterials, cells, and bioactive molecules for restoring physiological function and regenerating tissues and organs
Publication Details
Publication Date
2021-03-02
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