NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease
Консенсусная конференция NIH. Helicobacter pylori при язвенной болезни. Консенсусная экспертная группа NIH по Helicobacter pylori при язвенной болезни
1994-07-06
SCID: 54.1/5yp8emcn
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H pylori and gastric cancerH pylori eradicationHelicobacter pyloridiagnosis and treatmentpeptic ulcer disease
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Abstract (AI)
The National Institutes of Health Consensus Development Conference on<i>Helicobacter pylori</i>in Peptic Ulcer Disease brought together specialists in gastroenterology, surgery, infectious diseases, epidemiology, and pathology, as well as the public to address the following questions: (1) What is the causal relationship of<i>H pylori</i>to upper gastrointestinal disease? (2) How does one diagnose and eradicate<i>H pylori</i>infection? (3) Does eradication of<i>H pylori</i>infection benefit the patient with peptic ulcer disease? (4) What is the relationship between<i>H pylori</i>infection and gastric malignancy? (5) Which<i>H pylori</i>—infected patients should be treated? (6) What are the most important questions that must be addressed by future research in<i>H pylori</i>infections? Following 1½ days of presentations by experts and discussion by the audience, a consensus panel weighed the evidence and prepared their consensus statement. Among their findings, the consensus panel concluded that (1) ulcer patients with<i>H pylori</i>infection require treatment with antimicrobial agents in addition to antisecretory drugs whether on first presentation with the illness or on recurrence; (2) the value of treating of nonulcerative dyspepsia patients with<i>H pylori</i>infection remains to be determined; and (3) the interesting relationship between<i>H pylori</i>infection and gastric cancers requires further exploration. (<i>JAMA</i>. 1994;272:65-69)
Key Findings
1
Peptic ulcer patients infected with Helicobacter pylori require treatment with antimicrobial agents in addition to antisecretory drugs at first presentation and on recurrence.
2
The benefit of treating Helicobacter pylori infection in patients with nonulcerative dyspepsia remains uncertain and requires further determination.
3
The observed relationship between Helicobacter pylori infection and gastric cancer is notable but requires additional research to clarify its nature and implications.
Research Object
Helicobacter pylori infection in patients with peptic ulcer disease
Research Subject
Causal role, diagnosis, eradication, clinical benefit of eradication, and relationship to gastric malignancy of H. pylori infection in peptic ulcer disease
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1994-07-06
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