Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases
Активный туберкулёз, последствия и коинфекция COVID-19: первая когорта из 49 случаев
2020-05-26
SCID: 54.1/6ggbfpkn
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COVID-19SARS-CoV-2 co-infectionactive tuberculosisclinical outcomestuberculosis sequelae
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Abstract (AI)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) pandemic has attracted interest because of its global rapid spread, clinical severity, high mortality rate and capacity to overwhelm healthcare systems [1, 2]. SARS-CoV-2 transmission occurs mainly through droplets, although surface contamination contributes and debate continues on aerosol transmission [3–5]. Diagnostic, treatment and outcome details of 49 COVID-19 patients with concurrent or previous tuberculosis from 8 countries show varied clinical profiles <https://bit.ly/369ZGGu> The article is part of the scientific activities of the Global Tuberculosis Network (GTN); GREPI (Groupe de Recherche et d'Enseignement en Pneumo-Infectiologie), a working group from SPLF (Société de Pneumologie de Langue Française); SEPAR (Sociedad Española de Neumología and Cirugía Torácica); Moscow Society of Phtisiology and of the WHO Collaborating Centre for Tuberculosis and Lung Diseases, Tradate, ITA-80, 2017-2020- GBM/RC/LDA). Delia Goletti is a professor of Pathology at Unicamillus University in Rome, Italy. The authors wish to thank Enrico Girardi (National Institute for Infectious Diseases, L. Spallanzani, IRCCS, Rome, Italy) for the useful comments on the manuscript.
Key Findings
1
Findings are based on multicountry observational data collected through an international tuberculosis network and collaborating respiratory-infectious disease groups.
2
The cohort includes varied clinical presentations, diagnostic approaches, treatments, and outcomes among patients with COVID-19 and tuberculosis-related conditions.
3
The report describes the first cohort of 49 COVID-19 patients with concurrent active tuberculosis, prior tuberculosis, or tuberculosis sequelae across eight countries.
4
The study highlights the need to characterize interactions between SARS-CoV-2 infection and tuberculosis in patients with active or previous tuberculosis.
Research Object
COVID-19 patients with concurrent or previous tuberculosis
Research Subject
Their diagnostic, treatment, and clinical outcome profiles
Publication Details
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2020-05-26
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