Nano based drug delivery systems: recent developments and future prospects

Нанооснованные системы доставки лекарственных средств: современные достижения и перспективы развития
Solomon Habtemariam, Leonardo Fernandes Fraceto, Mallappa Kumara Swamy, Han-Seung Shin, Jayanta Kumar Patra, Gitishree Das, Estefânia Vangelie Ramos Campos, María del Pilar Rodríguez-Torres, Laura Susana Acosta‐Torres, L.A. Dı́az-Torres, Renato Grillo, Shivesh Sharma
2018-09-19

controlled releasenano-based drug delivery systemsnanomaterialsnanomedicinetargeted drug delivery
Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc.) in the treatment of various diseases. The current review, presents an updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs (e.g., natural products) and selective diagnosis through disease marker molecules. The opportunities and challenges of nanomedicines in drug delivery from synthetic/natural sources to their clinical applications are also discussed. In addition, we have included information regarding the trends and perspectives in nanomedicine area.
1
Clinical translation of nanomedicines involves opportunities and challenges spanning synthetic and natural drug sources, with future development guided by emerging trends and perspectives.
2
Nano-based delivery systems can improve site-specific and target-oriented treatment of chronic diseases by enabling precise drug administration.
3
Nanomaterials may enhance the efficacy of both established and novel drugs, including natural products, while supporting selective diagnosis through disease-marker molecules.
4
Nanomedicine uses nanoscale materials for diagnostic applications and controlled delivery of therapeutic agents to specific target sites.
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Recent applications include nanoscale delivery of chemotherapeutic, biological, and immunotherapeutic agents for treating diverse diseases.

Nano-based drug delivery systems (nanomedicines and nanomaterials used to deliver therapeutic and diagnostic agents)

recent advances, applications, efficacy improvement, targeted delivery, and clinical opportunities and challenges of nanomedicines

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2018-09-19
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Authors
Solomon Habtemariam
Leonardo Fernandes Fraceto
Mallappa Kumara Swamy
Han-Seung Shin
Jayanta Kumar Patra
Gitishree Das
Estefânia Vangelie Ramos Campos
María del Pilar Rodríguez-Torres
Laura Susana Acosta‐Torres
L.A. Dı́az-Torres
Renato Grillo
Shivesh Sharma
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