Metal artifact reduction sequence-MRI abnormalities in asymptomatic patients with dual-mobility hip prostheses

Отклонения в MARS-MRI у бессимптомных пациентов с двухподвижными тазобедренными протезами
Nathanael D. Heckmann, Jay R. Lieberman, Alexander B. Christ, Donald B. Longjohn, Brian Chung, Kevin C. Liu, Xiao T. Chen, Luke R. Lovro, Natalie M. Kistler, Eric A. White, Daniel A. Oakes
2024-03-01

dual-mobility hip prosthesesmetal artifact reduction sequence MRIperiprosthetic fluid collectionserum cobalt levels
Aims: Modular dual-mobility (DM) articulations are increasingly used during total hip arthroplasty (THA). However, concerns remain regarding the metal liner modularity. This study aims to correlate metal artifact reduction sequence (MARS)-MRI abnormalities with serum metal ion levels in patients with DM articulations. Methods: A total of 45 patients (50 hips) with a modular DM articulation were included with mean follow-up of 3.7 years (SD 1.2). Enrolled patients with an asymptomatic, primary THA and DM articulation with over two years' follow-up underwent MARS-MRI. Each patient had serum cobalt, chromium, and titanium levels drawn. Patient satisfaction, Oxford Hip Score, and Forgotten Joint Score-12 (FJS-12) were collected. Each MARS-MRI was independently reviewed by fellowship-trained musculoskeletal radiologists blinded to serum ion levels. Results: Overall, two patients (4.4%) had abnormal periprosthetic fluid collections on MARS-MRI with cobalt levels > 3.0 μg/l. Four patients (8.9%) had MARS-MRI findings consistent with greater trochanteric bursitis, all with cobalt levels < 1.0 μg/l. A seventh patient had a periprosthetic fluid collection with normal ion levels. Of the 38 patients without MARS-MRI abnormalities, 37 (97.4%) had cobalt levels < 1.0 μg/l, while one (2.6%) had a cobalt level of 1.4 μg/l. One patient (2.2%) had a chromium level > 3.0 μg/l and a periprosthetic fluid collection. Of the 41 patients with titanium levels, five (12.2%) had titanium levels > 5.0 μg/l without associated MARS-MRI abnormalities. Conclusion: Periprosthetic fluid collections associated with elevated serum cobalt levels in patients with asymptomatic DM articulations occur infrequently (4.4%), but further assessment is necessary due to implant heterogeneity.
1
Among patients without MARS-MRI abnormalities, 97.4% had cobalt levels < 1.0 μg/l, with only one patient having cobalt 1.4 μg/l.
2
Eight-point-nine percent of patients had MARS-MRI findings consistent with greater trochanteric bursitis, and all of these had cobalt levels < 1.0 μg/l.
3
In asymptomatic patients with modular dual-mobility hip articulations, 4.4% had abnormal periprosthetic fluid collections on MARS-MRI associated with cobalt levels > 3.0 μg/l.
4
One patient had a periprosthetic fluid collection despite normal serum metal ion levels, indicating imaging abnormalities can occur without elevated ions.
5
Overall, periprosthetic fluid collections linked to elevated serum cobalt in asymptomatic DM articulations are infrequent, but further assessment is needed due to implant heterogeneity.
6
Twelve-point-two percent of patients (5/41) had titanium levels > 5.0 μg/l without corresponding MARS-MRI abnormalities.

Asymptomatic patients with modular dual-mobility (DM) total hip arthroplasty articulations undergoing MARS-MRI

Correlation between MARS-MRI periprosthetic abnormalities (e.g., fluid collections, trochanteric bursitis) and serum metal ion levels (cobalt, chromium, titanium) in these patients

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2024-03-01
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Nathanael D. Heckmann
Jay R. Lieberman
Alexander B. Christ
Donald B. Longjohn
Brian Chung
Kevin C. Liu
Xiao T. Chen
Luke R. Lovro
Natalie M. Kistler
Eric A. White
Daniel A. Oakes
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