Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

Визуализация и фотодинамическая терапия: механизмы, мониторинг и оптимизация
Jonathan P. Celli, Bryan Q. Spring, Imran Rizvi, Conor L. Evans, Kimberley S. Samkoe, Sarika Verma, Brian W. Pogue, Tayyaba Hasan
2010-03-30

biomedical imagingphotodynamic therapytherapy mechanismstreatment monitoringtreatment optimization
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTImaging and Photodynamic Therapy: Mechanisms, Monitoring, and OptimizationJonathan P. Celli†, Bryan Q. Spring†, Imran Rizvi†‡, Conor L. Evans†, Kimberley S. Samkoe‡, Sarika Verma†, Brian W. Pogue†‡, and Tayyaba Hasan*†View Author Information Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, and Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755* To whom correspondence should be addressed. E-mail: [email protected]†Massachusetts General Hospital and Harvard Medical School.‡Dartmouth College.Cite this: Chem. Rev. 2010, 110, 5, 2795–2838Publication Date (Web):March 30, 2010Publication History Received4 September 2009Published online30 March 2010Published inissue 12 May 2010https://pubs.acs.org/doi/10.1021/cr900300phttps://doi.org/10.1021/cr900300preview-articleACS PublicationsCopyright © 2010 American Chemical SocietyRequest reuse permissionsArticle Views23102Altmetric-Citations1936LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Biological imaging,Cancer,Fluorescence,Fluorescence imaging,Tumors Get e-Alerts
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Imaging is presented as a means to monitor photosensitizer distribution, treatment response, and photodynamic therapy-associated biological processes.
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The article evaluates strategies for optimizing photodynamic therapy by integrating mechanistic understanding with imaging-based treatment monitoring.
3
The review examines the mechanisms underlying photodynamic therapy, including photosensitizer activation, reactive species generation, and tumor cell killing.
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The review highlights monitoring and optimization approaches intended to improve photodynamic therapy efficacy and enable more controlled treatment delivery.

photodynamic therapy and its associated imaging and monitoring systems

the mechanisms, monitoring approaches, and optimization of photodynamic therapy efficacy

Publication Details
Publication Date
2010-03-30
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Authors
Jonathan P. Celli
Bryan Q. Spring
Imran Rizvi
Conor L. Evans
Kimberley S. Samkoe
Sarika Verma
Brian W. Pogue
Tayyaba Hasan
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