Electrospinning for drug delivery applications: A review
Электроспиннинг для доставки лекарственных средств: обзор
2021-03-26
SCID: 54.1/8sehntmj
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drug deliveryelectrospinningelectrospun nanofibersnanofibrous meshespersonalized medicine
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Abstract (AI)
Drug delivery devices are promising tools in the pharmaceutical field, as they are able to maximize the therapeutic effects of the delivered drug while minimizing the undesired side effects. In the past years, electrospun nanofibers attracted rising attention due to their unique features, like biocompatibility and broad flexibility. Incorporation of active principles in nanofibrous meshes proved to be an efficient method for in situ delivery of a wide range of drugs, expanding the possibility and applicability of those devices. In this review, the principle of electrospinning and different fields of applications are treated to give an overview of the recent literature, underlining the easy tuning and endless combination of this technique, that in the future could be the new frontier of personalized medicine.
Key Findings
1
Electrospinning parameters and material combinations can be readily tuned, supporting applications across multiple drug-delivery fields.
2
Electrospun nanofibers are attracting increasing interest for drug delivery because of their biocompatibility and broad design flexibility.
3
Incorporating active pharmaceutical ingredients into electrospun nanofibrous meshes enables efficient in situ delivery of diverse drugs.
4
The review identifies electrospinning as a potentially important platform for personalized medicine through customizable drug-delivery devices.
Research Object
Electrospun nanofibrous drug-delivery devices incorporating active pharmaceutical ingredients
Research Subject
The tunability, versatility, and drug-delivery applications of electrospun nanofibrous meshes
Publication Details
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2021-03-26
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