Ultrasound‐guided injection of the iliopsoas muscle with botulinum toxin in camptocormia

Ультразвуковая инъекция ботулинического токсина в подвздошно-поясничную мышцу при камптокормии
Thomas Gasser, Friedrich Asmus, Rainer von Coelln, Armin Raible
2008-02-28

botulinum toxin Acamptocormiailiopsoas muscleparkinsonismultrasound-guided injection
Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco-lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound-guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500-1,500 MU of BTX per side in 4-6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow-up visits, as well as self-assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism-associated camptocormia.
1
A novel ultrasound-guided technique safely delivered botulinum toxin A into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia.
2
At the highest dose, all patients experienced mild weakness of hip flexion.
3
Iliopsoas botulinum toxin injection does not appear promising for parkinsonism-associated camptocormia.
4
Patients received 500–1,500 MU of botulinum toxin A per side at 4–6-month intervals, and treatment was generally well tolerated.
5
Standardized examinations and patient self-assessments showed no relevant or sustained improvement in trunk posture.

Parkinsonian patients with parkinsonism-associated camptocormia treated by ultrasound-guided botulinum toxin A injection into the iliopsoas muscle

Safety, tolerability, and therapeutic efficacy of iliopsoas BTX injection for improving camptocormia-related trunk flexion and posture

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2008-02-28
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Authors
Thomas Gasser
Friedrich Asmus
Rainer von Coelln
Armin Raible
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