Quantitative laws in biological chemistry
Количественные закономерности в биологической химии
1915-01-01
SCID: 54.1/95k848e7
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common logarithmsenzyme activitymicrobial toxinsquantitative biological chemistryreaction velocity
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Abstract (AI)
If now a variable quantity y is dependent upon another quantity x, which we may change as we wish, for instance temperature or concentration, so that the formula expressing this dependency possesses the form y = a + bx, where a and b are two experimentally determined constant values, then the graphical interpretation #=1-5.If we put x = 1, then y = a + 6, i.e. b is the distance of the point in which the straight line y = a + bx cuts a vertical line x = 1 going through the point 1 of the ^r-axis, from a horizontal line 1 It would be more exact to use natural logarithms instead of the common ones.With natural logarithms the value of b (the velocity of reaction) is 2-3 times greater than with common logarithms, which are still generally used on account of their convenience.In the following we always use common logarithms.This method is preferred as soon as the functions f(z) or p{tt) are at all complicated, so that we are not so great that we cannot use the straight line as a true expression of the observed data, but make use of the representation of the strict formula.But even in this case we use log K, and not K itself, for the representation, because the curve then has a nearly rectilinear form, that is, its curvature is very insignificant, and the smaller the curvature is, the clearer is the representation given by the curve to the eye, and correspondingly, the easier it is soluble sugar maltose.Then glands in the walls of the stomach secrete the stomachical juice, which con- tains two active substances, the pepsin, which decomposes the albuminous substances of the food into furnished by the yeast-cells, namely, zymase, which causes alcoholic fermentation ; invertase, which de- composes cane -sugar ; and maltase, which splits up maltose.In general, micro-organisms produce a large number of substances of high chemical activity.Amongst these a great many are of the highest interest for us, as, for instance, the diphtheria toxin or the tetanus-poison, which cause the terrible diseases diphtheria and lock-jaw.Even higher organisms, as snakes or spiders or insects, produce similar poisons, as do also some plants, e.g.Abrus praeca-VELOCITY OF REACTIONS Dried rennet is extremely slowly decomposed at that temperature.
Key Findings
1
Biological chemistry is illustrated through enzymatic and microbial activities, including pepsin digestion, zymase-driven fermentation, invertase action, maltase activity, and toxin production.
2
Common logarithms are used for convenience, although natural logarithms yield velocity values 2–3 times greater.
3
Graphical interpretation is presented as a practical method for estimating constants and reaction velocities from experimental data.
4
Logarithmic representation, particularly plotting log K rather than K, reduces curvature and improves visual interpretation of complex functions.
5
The abstract emphasizes representing experimentally determined relationships using linear equations of the form y = a + bx when applicable.
Research Object
biological chemical reactions and biologically active substances, including digestive enzymes, microbial enzymes, and toxins
Research Subject
quantitative relationships between variable conditions and chemical activity or reaction rates
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1915-01-01
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