Exploring treatment options in cancer: tumor treatment strategies
Изучение вариантов лечения рака: стратегии лечения опухолей
2024-07-16
SCID: 54.1/a5634mc9
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Antibody-drug conjugatesCell-based therapiesGene therapyPeptide drugsSmall-molecule targeted agents
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Abstract (AI)
Traditional therapeutic approaches such as chemotherapy and radiation therapy have burdened cancer patients with onerous physical and psychological challenges. Encouragingly, the landscape of tumor treatment has undergone a comprehensive and remarkable transformation. Emerging as fervently pursued modalities are small molecule targeted agents, antibody-drug conjugates (ADCs), cell-based therapies, and gene therapy. These cutting-edge treatment modalities not only afford personalized and precise tumor targeting, but also provide patients with enhanced therapeutic comfort and the potential to impede disease progression. Nonetheless, it is acknowledged that these therapeutic strategies still harbour untapped potential for further advancement. Gaining a comprehensive understanding of the merits and limitations of these treatment modalities holds the promise of offering novel perspectives for clinical practice and foundational research endeavours. In this review, we discussed the different treatment modalities, including small molecule targeted drugs, peptide drugs, antibody drugs, cell therapy, and gene therapy. It will provide a detailed explanation of each method, addressing their status of development, clinical challenges, and potential solutions. The aim is to assist clinicians and researchers in gaining a deeper understanding of these diverse treatment options, enabling them to carry out effective treatment and advance their research more efficiently.
Key Findings
1
Cancer treatment is shifting from conventional chemotherapy and radiotherapy toward more precise and personalized modalities.
2
Despite substantial promise, emerging therapies retain limitations and untapped potential requiring further development.
3
Small-molecule targeted drugs, peptide drugs, antibody drugs including ADCs, cell therapy, and gene therapy are reviewed as emerging treatment options.
4
The review examines development status, clinical challenges, and potential solutions to inform clinical practice and foundational research.
5
These modalities may improve therapeutic comfort, enable tumor-specific targeting, and potentially impede disease progression.
Research Object
Tumor treatment modalities (small molecule targeted agents, antibody-drug conjugates, peptide and antibody drugs, cell-based therapies, and gene therapy)
Research Subject
the development status, clinical challenges, advantages, limitations, and potential solutions of these tumor treatment modalities
Publication Details
Publication Date
2024-07-16
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