Production of secondary metabolites using tissue culture-based biotechnological applications

Получение вторичных метаболитов с использованием биотехнологических методов на основе культуры тканей
İbrahim İlker Özyiğit, İlhan Doğan, Aslı Hocaoğlu-Özyiğit, Bestenur Yalçın, Ayşegül Erdoğan, İbrahim Ertuğrul Yalçın, Evren Cabi, Yılmaz Kaya
2023-06-29

gene transferplant biotechnologyplant tissue culturesecondary metabolitestransgenic plants
Plants are the sources of many bioactive secondary metabolites which are present in plant organs including leaves, stems, roots, and flowers. Although they provide advantages to the plants in many cases, they are not necessary for metabolisms related to growth, development, and reproduction. They are specific to plant species and are precursor substances, which can be modified for generations of various compounds in different plant species. Secondary metabolites are used in many industries, including dye, food processing and cosmetic industries, and in agricultural control as well as being used as pharmaceutical raw materials by humans. For this reason, the demand is high; therefore, they are needed to be obtained in large volumes and the large productions can be achieved using biotechnological methods in addition to production, being done with classical methods. For this, plant biotechnology can be put in action through using different methods. The most important of these methods include tissue culture and gene transfer. The genetically modified plants are agriculturally more productive and are commercially more effective and are valuable tools for industrial and medical purposes as well as being the sources of many secondary metabolites of therapeutic importance. With plant tissue culture applications, which are also the first step in obtaining transgenic plants with having desirable characteristics, it is possible to produce specific secondary metabolites in large-scale through using whole plants or using specific tissues of these plants in laboratory conditions. Currently, many studies are going on this subject, and some of them receiving attention are found to be taken place in plant biotechnology and having promising applications. In this work, particularly benefits of secondary metabolites, and their productions through tissue culture-based biotechnological applications are discussed using literature with presence of current studies.
1
Genetically modified plants can improve agricultural productivity and commercial value while serving as sources of therapeutically important secondary metabolites.
2
High industrial and pharmaceutical demand requires large-volume production, which can be supported by plant biotechnology alongside conventional cultivation and extraction.
3
Plant secondary metabolites are bioactive, species-specific compounds found across plant organs and widely used in pharmaceutical, food, dye, cosmetic, and agricultural applications.
4
Tissue culture enables laboratory-scale or large-scale production of specific secondary metabolites using whole plants or selected plant tissues.
5
Tissue culture is also an important initial step for generating transgenic plants with desirable traits through gene transfer.

Plant tissue culture systems used for the production of plant secondary metabolites

Large-scale production of bioactive secondary metabolites and the effects of tissue culture-based biotechnological applications on their production

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2023-06-29
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Authors
İbrahim İlker Özyiğit
İlhan Doğan
Aslı Hocaoğlu-Özyiğit
Bestenur Yalçın
Ayşegül Erdoğan
İbrahim Ertuğrul Yalçın
Evren Cabi
Yılmaz Kaya
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