SELECTIVE CLEAVAGE OF THE METHIONYL PEPTIDE BONDS IN RIBONUCLEASE WITH CYANOGEN BROMIDE<sup>1</sup>
Селективный разрыв метиониловых пептидных связей в рибонуклеазе бромцианом
1961-03-01
SCID: 54.1/aqh4tyeq
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Erhard Gross and Bernhard Witkopcyanogen bromidemethionyl peptide bondsribonucleaseselective cleavage
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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSELECTIVE CLEAVAGE OF THE METHIONYL PEPTIDE BONDS IN RIBONUCLEASE WITH CYANOGEN BROMIDE1Erhard Gross and Bernhard WitkopCite this: J. Am. Chem. Soc. 1961, 83, 6, 1510–1511Publication Date (Print):March 1, 1961Publication History Published online1 May 2002Published inissue 1 March 1961https://pubs.acs.org/doi/10.1021/ja01467a052https://doi.org/10.1021/ja01467a052research-articleACS PublicationsRequest reuse permissionsArticle Views587Altmetric-Citations380LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Key Findings
1
Cyanogen bromide selectively cleaves peptide bonds at methionyl residues in ribonuclease.
2
Selective methionyl bond cleavage produces defined peptide fragments of ribonuclease.
3
The method provides a chemical means to map protein sequence by targeting methionine sites.
Research Object
Ribonuclease protein undergoing selective cleavage at methionyl peptide bonds by cyanogen bromide
Research Subject
Selective cleavage of methionyl peptide bonds in ribonuclease mediated by cyanogen bromide
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1961-03-01
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