SOME CLINICAL ASPECTS AND COMPARATIVE CHARACTERISTICS OF ENTEROPATHOGENIC AND ENTEROINVASIVE ESCHERICHIA COLIINFECTIONIN CHILDREN

Некоторые клинические аспекты и сравнительная характеристика инфекции Escherichia coli энтеропатогенной и энтероинвазивной природы у детей
B.I. Buribayeve, I.A. Kasimov, Zilola Xalilova
2021-03-30

ColitisComplications: hypovolemic shock, acute renal failure, infectious toxic shock, neurotoxicosis, disseminated intravascular coagulationEnteroinvasive Escherichia coli (EIEC)Enteropathogenic Escherichia coli (EPEC)Secretory diarrhea
The clinical course of enteropathogenic (EPEC) and enteroinvasive escherichiosis (EIEC) in children was studied and their comparative characteristics were carried out. We examined 82 sick children with early age Escherichiosis, caused in 28 byenteroinvasive, in 54 with enteropathogenic strains. In children with EPEC, secretory diarrhea was observed, and EIEC —colitis. A more pronounced manifestation of intoxication syndrome was observed in children with EPEC. The manifestations of diarrheal syndrome and electrolyte disturbances, assessed by the degree of dehydration, are more typical for children with EPEC. If in children with EPEC such complications as hypovolemic shock and acute renal failure were encountered, then in children with EIEC in the form of complications of infectious toxic shock, neurotoxicosis and disseminated intravascular coagulation.
1
Children with EPEC showed more pronounced manifestations of intoxication syndrome than those with EIEC.
2
Complications differed by pathogen: EPEC cases included hypovolemic shock and acute renal failure, while EIEC cases included infectious toxic shock, neurotoxicosis, and disseminated intravascular coagulation.
3
Diarrheal syndrome severity and electrolyte disturbances (degree of dehydration) were more typical and pronounced in children with EPEC.
4
EPEC infection predominantly produced secretory diarrhea, whereas EIEC infection predominantly produced colitis.
5
Study examined 82 children with early-age escherichiosis: 54 with enteropathogenic E. coli (EPEC) and 28 with enteroinvasive E. coli (EIEC).

Enteropathogenic (EPEC) and enteroinvasive (EIEC) Escherichia coli infection in children

Comparative clinical course and characteristics including diarrheal and intoxication syndromes, electrolyte disturbances/dehydration, and complications (hypovolemic shock, acute renal failure, infectious toxic shock, neurotoxicosis, disseminated intravascular coagulation) between EPEC and EIEC infections

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2021-03-30
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B.I. Buribayeve
I.A. Kasimov
Zilola Xalilova
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