Phaeosphaeride A, an Inhibitor of STAT3-Dependent Signaling Isolated from an Endophytic Fungus

Феозфаерид A — ингибитор сигнальной передачи, зависящей от STAT3, выделенный из эндофитного гриба
Jon Clardy, Sean F. Brady, Frank C. Schroeder, Katherine N. Maloney, Wenshan Hao, Jun Xu, Jay Gibbons, John A. Hucul, Deborah M. Roll
2006-08-01
SCID:  54.1/b27b9y6t Discuss with AI
Phaeosphaeride ASTAT3-dependent signalingendophytic fungusnitrogen-containing bicyclic compound
Abstract (AI)
Phaeosphaeride A, a nitrogen-containing bicyclic compound produced by an endophytic fungus, inhibits signaling by the transcription factor STAT3.
Key Findings
1
Phaeosphaeride A inhibits signaling mediated by the transcription factor STAT3.
2
Phaeosphaeride A is a nitrogen-containing bicyclic compound isolated from an endophytic fungus.
3
The compound represents a natural-product inhibitor targeting STAT3-dependent signaling pathways.
Research Object

Phaeosphaeride A, a nitrogen-containing bicyclic compound produced by an endophytic fungus

Research Subject

Inhibition of STAT3-dependent signaling by Phaeosphaeride A

Publication Details
Publication Date
2006-08-01
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Authors
Jon Clardy
Sean F. Brady
Frank C. Schroeder
Katherine N. Maloney
Wenshan Hao
Jun Xu
Jay Gibbons
John A. Hucul
Deborah M. Roll
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