Overview of Carbon Nanotubes for Biomedical Applications

Обзор углеродных нанотрубок для биомедицинских применений
Juliette Simon, Emmanuel Flahaut, Muriel Golzio
2019-02-20

biomedical applicationscarbon nanotube-based hydrogelscarbon nanotubestargeted drug deliverytissue engineering
The unique combination of mechanical, optical and electrical properties offered by carbon nanotubes has fostered research for their use in many kinds of applications, including the biomedical field. However, due to persisting outstanding questions regarding their potential toxicity when considered as free particles, the research is now focusing on their immobilization on substrates for interface tuning or as biosensors, as load in nanocomposite materials where they improve both mechanical and electrical properties or even for direct use as scaffolds for tissue engineering. After a brief introduction to carbon nanotubes in general and their proposed applications in the biomedical field, this review will focus on nanocomposite materials with hydrogel-based matrices and especially their potential future use for diagnostics, tissue engineering or targeted drug delivery. The toxicity issue will also be briefly described in order to justify the safe(r)-by-design approach offered by carbon nanotubes-based hydrogels.
1
Carbon nanotubes combine mechanical, optical, and electrical properties that support diverse biomedical applications.
2
Carbon nanotubes incorporated into nanocomposites can enhance both mechanical and electrical properties, including in hydrogel-based matrices.
3
Carbon nanotube–based hydrogels are highlighted as promising platforms for diagnostics, tissue engineering, and targeted drug delivery.
4
Embedding carbon nanotubes in hydrogels supports a safer-by-design strategy intended to reduce risks associated with free-particle exposure.
5
Persistent toxicity concerns about free carbon nanotube particles have shifted research toward immobilized, composite, or scaffold-based configurations.

carbon nanotube-based hydrogel nanocomposite materials for biomedical applications

their biomedical functionality and safer-by-design potential, including diagnostic, tissue-engineering, and targeted drug-delivery applications, with consideration of toxicity

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2019-02-20
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Juliette Simon
Emmanuel Flahaut
Muriel Golzio
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