Heavy metal pollution in the environment and their toxicological effects on humans

Загрязнение окружающей среды тяжелыми металлами и их токсикологическое воздействие на человека
Jessica Briffa, Emmanuel Sinagra, Renald Blundell, Jessica F. Briffa
2020-09-01

bioaccumulation in humansenvironmental contamination (water, soil, atmosphere)heavy metal pollutionsources: agriculture, metal industries, fertilizers, pesticides, improper waste disposaltoxicological effects / pharmacokinetics
Environmental pollution of heavy metals is increasingly becoming a problem and has become of great concern due to the adverse effects it is causing around the world. These inorganic pollutants are being discarded in our waters, soils and into the atmosphere due to the rapidly growing agriculture and metal industries, improper waste disposal, fertilizers and pesticides. This review shows how pollutants enter the environment together with their fate. Some metals affect biological functions and growth, while other metals accumulate in one or more different organs causing many serious diseases such as cancer. The pharmacokinetics and toxicological processes in humans for each metal is described. In summary, the review shows the physiological and biochemical effects of each heavy metal bioaccumulation in humans and the level of gravity and disquieting factor of the disease.
1
Different heavy metals have distinct fates in the environment and can enter biological systems through environmental exposure pathways.
2
Heavy metal pollution is a growing global problem caused by agriculture, metal industries, improper waste disposal, fertilizers, and pesticides contaminating water, soil, and air.
3
Some heavy metals impair biological functions and growth, while others bioaccumulate in specific organs, leading to serious diseases including cancer.
4
The overall assessment emphasizes the severity and alarming public-health implications of human heavy metal bioaccumulation.
5
The review summarizes pharmacokinetics and toxicological processes of individual heavy metals in humans, linking bioaccumulation to physiological and biochemical effects.

Environmental heavy metals pollution (heavy metals in water, soil and air)

Toxicological effects, pharmacokinetics, bioaccumulation, physiological and biochemical impacts of each heavy metal on humans and their disease outcomes

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Publication Date
2020-09-01
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Authors
Jessica Briffa
Emmanuel Sinagra
Renald Blundell
Jessica F. Briffa
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