Chemical Constituents of Prangos tschimganica; Structure Elucidation and Absolute Configuration of Coumarin and Furanocoumarin Derivatives with Anti-HIV Activity.
Химические компоненты Prangos tschimganica; установление структуры и абсолютной конфигурации производных кумарина и фуранокумарина с анти-ВИЧ-активностью
2001-01-01
SCID: 54.1/d9w57zs6
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Prangos tschimganicaanti-HIV activitycoumarin derivativesfuranocoumarin derivativesmodified Mosher's method
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Abstract (AI)
The methanol extract of the dried aerial parts of Prangos tschimganica gave three new coumarin derivatives and 30 known coumarin derivatives. Their structures were established on the basis of chemical and spectroscopic evidence. Absolute configuration of the isolated compounds were determined by using a modified Mosher's method. Some of the isolated compounds showed anti-HIV activity.
Key Findings
1
Absolute configurations of the isolated compounds were determined using a modified Mosher’s method.
2
Methanol extraction of Prangos tschimganica aerial parts yielded three new and 30 previously known coumarin derivatives.
3
Some isolated compounds demonstrated anti-HIV activity.
4
The structures of the isolated coumarin and furanocoumarin compounds were established using chemical and spectroscopic evidence.
Research Object
Coumarin and furanocoumarin derivatives isolated from the methanol extract of the dried aerial parts of Prangos tschimganica
Research Subject
Their chemical structures, absolute configurations, and anti-HIV activity
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2001-01-01
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