Branch Retinal Vein Occlusion, Macular Ischemia, and Intravitreal Anti-VEGF Therapy

Окклюзия ветви центральной вены сетчатки, ишемия макулы и интравитреальная терапия препаратами анти-VEGF
Thomas Bertelmann, Hans Ulrich Frank, Hendrik Ansgar Fuchs, Nicolas Feltgen
2017-04-28

Branch retinal vein occlusionCentral retinal thicknessIntravitreal anti-VEGF therapyIschemic macular edemaMacular ischemia
PURPOSE: To report a case with ischemic macular edema (ME) due to an acute branch retinal vein occlusion (BRVO) which was treated with repeated intravitreal anti-VEGF injections. METHODS: Retrospective case presentation. RESULTS: A 66-year-old female patient was treated with repeated intravitreal anti-VEGF injections due to ischemic ME following an acute BRVO. Over a period of 2.5 years best corrected visual acuity increased from 0.06 to 0.6 (decimal notation) accompanied by a reduction in central retinal thickness from 546 to 292 µm. Overall 17 anti-VEGF injections were administered to treat repeated recurrence of ME. Macular ischemia did not worsen during this profound intravitreal anti-VEGF therapy. CONCLUSION: Intravitreal anti-VEGF therapy can be a beneficial treatment strategy even in ischemic ME following an acute BRVO.
1
A 66-year-old woman with ischemic macular edema after acute branch retinal vein occlusion received repeated intravitreal anti-VEGF therapy.
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Despite intensive anti-VEGF treatment, macular ischemia did not worsen.
3
Over 2.5 years, best-corrected visual acuity improved from 0.06 to 0.6 while central retinal thickness decreased from 546 to 292 µm.
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Seventeen anti-VEGF injections were administered for recurrent macular edema during follow-up.
5
The case suggests intravitreal anti-VEGF therapy may benefit ischemic macular edema following acute branch retinal vein occlusion.

Ischemic macular edema following acute branch retinal vein occlusion treated with repeated intravitreal anti-VEGF injections

The effects and therapeutic benefits of repeated intravitreal anti-VEGF therapy on macular ischemia, recurrent macular edema, visual acuity, and central retinal thickness

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2017-04-28
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Thomas Bertelmann
Hans Ulrich Frank
Hendrik Ansgar Fuchs
Nicolas Feltgen
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