Metal complexes as a promising source for new antibiotics

Металлические комплексы как перспективный источник новых антибиотиков
Angelo Frei, Johannes Zuegg, Alysha G. Elliott, Murray V. Baker, Stefan Braese, Christopher A. Brown, Feng Chen, Christopher G. Dowson, Gilles Dujardin, Nicole Jung, Anna King, Ahmed M. Mansour, Massimiliano Massi, John Moat, Heba Mohamed, Anna K. Renfrew, Peter J. Rutledge, Peter J. Sadler, Matthew H. Todd, Charlotte E. Willans, Justin J. Wilson, Matthew A. Cooper, Mark A. T. Blaskovich
2020-01-01

MRSAantimicrobial propertiesantimicrobial resistancemetal complexesnew antibiotics
(MRSA). 23 of these complexes have not been reported for their antimicrobial properties before. This work reveals the vast diversity that metal-containing compounds can bring to antimicrobial research. It is important to raise awareness of these types of compounds for the design of truly novel antibiotics with potential for combatting antimicrobial resistance.
1
Among the examined compounds, 23 metal complexes had not previously been reported for antimicrobial properties.
2
Metal-containing compounds offer substantial chemical diversity for antimicrobial research and antibiotic discovery.
3
The findings support increasing attention to metal complexes when designing novel antibiotics to address antimicrobial resistance.
4
The study evaluates metal complexes as potential sources of new antibiotics, particularly against MRSA.

metal complexes

antimicrobial properties and potential as new antibiotics against antimicrobial-resistant bacteria

Publication Details
Publication Date
2020-01-01
Journal
Publisher
ISSN
Access Type
Author Information
Authors
Angelo Frei
Johannes Zuegg
Alysha G. Elliott
Murray V. Baker
Stefan Braese
Christopher A. Brown
Feng Chen
Christopher G. Dowson
Gilles Dujardin
Nicole Jung
Anna King
Ahmed M. Mansour
Massimiliano Massi
John Moat
Heba Mohamed
Anna K. Renfrew
Peter J. Rutledge
Peter J. Sadler
Matthew H. Todd
Charlotte E. Willans
Justin J. Wilson
Matthew A. Cooper
Mark A. T. Blaskovich
Explore further
Open the scid.ai AI chat with a ready-made request: it will find papers on a similar topic and help build a literature review.
Find similar papers in the chat
Make a presentation
100%