Cerebral palsy: not always what it seems

Церебральный паралич: не всегда то, чем кажется
Rajat Das Gupta
2001-11-01

Brain MRICerebral palsyMetabolic disordersNeurodegenerative disordersNeurological syndrome
Cerebral palsy (CP) is not a disease, but a neurological syndrome, a combination of signs and symptoms, some of which may occur in neurodegenerative or metabolic disorders, particularly those with an onset in the first 2 years of life. There are many different causes of the syndrome. All children with CP should undergo brain MRI, even with an identified antenatal or perinatal insult. Children with CP should be referred to a paediatric neurologist or a clinical geneticist, or both, if appropriate and particularly in the absence of a known perinatal cerebral insult, with brain MRI that is reported to be normal, a progression in, or new, signs or where there is a reported 'family history of CP'. Finally, a few of the CP syndromes may be readily treatable and potentially prevent irreversible neurological and cognitive impairment.
1
Because CP has diverse causes, all children diagnosed with CP should undergo brain MRI, even when an antenatal or perinatal insult is identified.
2
Cerebral palsy is a neurological syndrome rather than a single disease, and its signs can overlap with early-onset neurodegenerative or metabolic disorders.
3
Referral to a paediatric neurologist or clinical geneticist is especially appropriate when no perinatal insult is known, MRI is normal, signs progress or newly appear, or CP occurs in the family.
4
Some CP-like syndromes are treatable, making accurate diagnosis important for preventing irreversible neurological and cognitive impairment.

Cerebral palsy syndrome in children, including cases potentially caused by neurodegenerative or metabolic disorders

Diagnostic differentiation of cerebral palsy from progressive or treatable neurodegenerative and metabolic disorders, including indications for brain MRI and specialist referral

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2001-11-01
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Rajat Das Gupta
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