2-Pyridone Synthesis Using 2-(Phenylsulfinyl)acetamide
Синтез 2-пиридонов с использованием 2-(фенилсульфинил)ацетамида
2012-12-18
SCID: 54.1/g8y7jm2k
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1,4-addition to α,β-unsaturated ketones2-(Phenylsulfinyl)acetamide2-Pyridone synthesiscyclization and sulfoxide elimination
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Abstract (AI)
2-Pyridones were prepared by means of an efficient protocol including the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination.
Key Findings
1
An efficient protocol was developed to synthesize 2-pyridones from α,β-unsaturated ketones
2
Subsequent cyclization of the 1,4-addition product is followed by sulfoxide elimination to furnish 2-pyridones
3
The method uses 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones as the initial step
4
The overall sequence (1,4-addition, cyclization, sulfoxide elimination) provides a concise route to 2-pyridones
Research Object
Synthesis of 2-pyridones via reaction of 2-(phenylsulfinyl)acetamide with α,β-unsaturated ketones
Research Subject
Efficient reaction protocol encompassing 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination to produce 2-pyridones
Publication Details
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2012-12-18
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