Shifting the limits in wheat research and breeding using a fully annotated reference genome
Расширение границ исследований и селекции пшеницы с использованием полностью аннотированного эталонного генома
2018-08-17
SCID: 54.1/hshht4k3
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annotated reference genomecoexpression networksgenomics-assisted breedinghexaploid bread wheat genomewheat transcriptome atlas
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Abstract (AI)
An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
Key Findings
1
A developmental transcriptome atlas enabled identification of tissue- and developmental-stage-specific gene coexpression networks.
2
An annotated hexaploid wheat reference genome was organized into 21 pseudomolecules spanning the A, B, and D subgenomes.
3
Subgenome-resolved analysis revealed the dynamics of complex gene families associated with environmental adaptation and end-use quality.
4
The assembly covers an estimated 94% of the wheat genome and contains 107,891 high-confidence gene models.
5
The resource contextualized genomic features with known agronomic single-gene loci and quantitative trait loci, supporting genomics-assisted wheat breeding.
Research Object
Fully annotated reference genome assembly of hexaploid bread wheat (21 pseudomolecules, A/B/D subgenomes)
Research Subject
the genomic organization, gene-expression networks, and adaptive and end-use-quality gene-family dynamics underlying wheat biology and genomics-assisted breeding
Publication Details
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2018-08-17
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