Sex-Related Differences in Plasma Oxytocin Levels in Humans
Гендерные различия уровней окситоцина в плазме крови человека
2019-03-26
SCID: 54.1/hsyu796t
Discuss with AI
humansplasma oxytocin levelsradioimmunoassaysex-related differencessocial emotions
Figures from the paper
Abstract (AI)
BACKGROUND: Increasing evidence supports a key role of Oxytocin (OT) as a modulator of social relationships in mammals. OBJECTIVE: The aim of the present study was to investigate possible sex-related differences in plasma OT levels in human beings. METHODS: Forty-five healthy men and 45 women (mean age: 34.9 ± 6.2 years), were included in the study. Plasma preparation, peptide extraction and OT radioimmunoassay were carried out according to standardized methods. RESULTS: The results showed that OT plasma levels (pg / ml, mean ± SD) were significantly higher in women than in men (4.53 ± 1.18 vs 1.53 ± 1.19, p ˂ 0.001). CONCLUSIONS: The present finding demonstrates sex-related differences in plasma OT levels in humans. It is tempting to hypothesize that such differences might be related to behaviours, attitudes, as well as susceptibility to stress response, resilience and social emotions specific of women and men.
Key Findings
1
The authors suggest that these differences may relate to sex-specific behavior, attitudes, stress susceptibility, resilience, and social emotions.
2
The findings demonstrate sex-related differences in circulating plasma oxytocin levels among humans.
3
The study compared plasma oxytocin levels in 45 healthy men and 45 healthy women using standardized extraction and radioimmunoassay methods.
4
Women had significantly higher mean plasma oxytocin levels than men: 4.53 ± 1.18 versus 1.53 ± 1.19 pg/ml (p < 0.001).
Research Object
Plasma oxytocin levels in healthy human men and women
Research Subject
Sex-related differences in plasma oxytocin levels
Publication Details
Publication Date
2019-03-26
Journal
Publisher
ISSN
Open access PDF
Access Type
Author Information
Download PDF
Subscribe to digest