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Tsiros, Georgios, Jelastopulu, Eleni, Sarafis, Pavlos, Tsirou, A., Malliarou, Maria, Domeyer, Philip R.
2018-03-01

K-SADS-PLattention-deficit/hyperactivity disorderdisruptive mood dysregulation disorderemotion dysregulationfamily history of ADHD
Background.-Emotion dysregulation, is common in ADHD and may arise from deficits in orienting toward and processing emotional stimuli It, Disruptive mood dysregulation(DMDD) in the offspring of parents with ADHD under estimated and this but the specificity of this association has not been established.Aims.-We examined the specificity of DMDD to family history by comparing offspring of parents with ADHD WITH a control group without psychiatric disorders.Method.-112 children who are offspring of parents with ADHD and 100 children for normal parents without ant psychiatric disorders and age and sex matched.We diagnose DMDD using the Schedule for Affective Disorders and Schizophrenia for School Aged Children for DSM-5 in 180 youth aged 6-18 years (KSADS-Pl).Results.-Diagnostic criteria for DMDD were met in 21 (18.75%) of the offspring of parents with bipolar disorder, 6 (6%) of the control offspring.With P-value < 0.001.Conclusions.-Ourresults suggest that Disruptive mood dysregulation (DMDD) is may be associated with a family history of ADHD.
1
Among 112 offspring of parents with ADHD, 21 children (18.75%) met diagnostic criteria for disruptive mood dysregulation disorder (DMDD).
2
Only 6% of control offspring of parents without psychiatric disorders met DMDD criteria, indicating a substantially lower prevalence than in the ADHD-family-history group.
3
The difference in DMDD prevalence between groups was statistically significant (P < 0.001).
4
The findings suggest that DMDD may be associated with a family history of ADHD, although the abstract does not establish the specificity of this association.
5
The study assessed 180 youth aged 6–18 years using the DSM-5 Schedule for Affective Disorders and Schizophrenia for School-Aged Children (K-SADS-PL).

Children aged 6–18 years who are offspring of parents with ADHD, compared with children of parents without psychiatric disorders

The prevalence and familial specificity of disruptive mood dysregulation disorder (DMDD) in relation to parental ADHD history

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2018-03-01
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Tsiros, Georgios
Jelastopulu, Eleni
Sarafis, Pavlos
Tsirou, A.
Malliarou, Maria
Domeyer, Philip R.
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