Practical Synthesis of Sultams via Sulfonamide Dianion Alkylation: Application to the Synthesis of Chiral Sultams

Практический синтез султамов посредством алкилирования дианиона сульфонамида: применение к синтезу хиральных султамов
Robert A. Reamer, Jaemoon Lee, Yong‐Li Zhong, David Askin
2003-10-01

chiral auxiliarieschiral sultamsintramolecular alkylationsulfonamide dianion alkylationsultams
[reaction: see text]. A practical synthesis of sultams was developed via intramolecular sulfonamide dianion alkylation. This method has been applied toward the synthesis of chiral sultams, which are synthetically valuable as chiral auxiliaries.
1
Chiral sultams produced are synthetically valuable as chiral auxiliaries
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Developed a practical synthesis of sultams via intramolecular sulfonamide dianion alkylation
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Method is applicable to the synthesis of chiral sultams

Sultams synthesized via intramolecular sulfonamide dianion alkylation

Practical synthetic method (intramolecular sulfonamide dianion alkylation) and its application to produce chiral sultams as chiral auxiliaries

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2003-10-01
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Authors
Robert A. Reamer
Jaemoon Lee
Yong‐Li Zhong
David Askin
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