The future of forensic DNA analysis

Будущее судебно-экспертного анализа ДНК
John M. Butler
2015-06-22

Rapid DNA testingfamilial DNA searchingforensic DNA analysisnext-generation sequencingshort tandem repeat loci
The author's thoughts and opinions on where the field of forensic DNA testing is headed for the next decade are provided in the context of where the field has come over the past 30 years. Similar to the Olympic motto of 'faster, higher, stronger', forensic DNA protocols can be expected to become more rapid and sensitive and provide stronger investigative potential. New short tandem repeat (STR) loci have expanded the core set of genetic markers used for human identification in Europe and the USA. Rapid DNA testing is on the verge of enabling new applications. Next-generation sequencing has the potential to provide greater depth of coverage for information on STR alleles. Familial DNA searching has expanded capabilities of DNA databases in parts of the world where it is allowed. Challenges and opportunities that will impact the future of forensic DNA are explored including the need for education and training to improve interpretation of complex DNA profiles.
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Familial DNA searching has expanded the investigative utility of DNA databases in jurisdictions where it is permitted, while complex profile interpretation requires improved education and training.
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Forensic DNA protocols are expected to become faster, more sensitive, and more powerful for investigations over the next decade.
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New short tandem repeat loci have expanded the core genetic marker sets used for human identification in Europe and the United States.
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Next-generation sequencing could provide greater coverage and more detailed information about STR alleles.
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Rapid DNA testing is nearing practical deployment and may enable new forensic applications.

forensic DNA analysis and testing for human identification

future developments in forensic DNA protocols, genetic markers, sequencing, database searching, and interpretation of complex DNA profiles

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2015-06-22
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John M. Butler
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