Neuroepithelial Tumor with AAV Integration after Intracisternal Magna Vector Delivery
Нейроэпителиальная опухоль с интеграцией AAV после доставки в суммума-церебелиарное пространство (intracisternal magna)
2026-05-13
SCID: 54.1/k4x89ueq
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AAV integrationPLAG1 fusionchimeric AAV-PLAG1 transcriptintracisternal magna vector deliveryneuroepithelial tumor
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Abstract (AI)
and expression of a chimeric AAV-PLAG1 transcript.
Key Findings
1
Detection of a neuroepithelial tumor associated with AAV integration following intracisternal magna AAV vector delivery.
2
Identification of AAV integration into the host genome linked to expression of a chimeric AAV-PLAG1 transcript.
3
Observation implies that intracisternal magna AAV delivery can lead to insertional events producing oncogenic chimeric transcripts.
Research Object
Neuroepithelial tumor arising after intracisternal magna AAV vector delivery
Research Subject
AAV integration and expression of a chimeric AAV-PLAG1 transcript in the tumor following intracisternal magna vector delivery
Publication Details
Publication Date
2026-05-13
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