Recent advances in the medical applications of hemostatic materials
Недавние достижения в медицинском применении гемостатических материалов
2022-11-29
SCID: 54.1/kx3pvkgq
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hemostasis in tumor surgeryhemostatic materialsnanofibersnatural polymerssynthetic polymers
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Abstract (AI)
Bleeding caused by trauma or surgery is a serious health problem, and uncontrollable bleeding can result in death. Therefore, developing safe, effective, and convenient hemostatic materials is important. Active hemostatic agents currently used to investigate the field of hemostasis are divided into four broad categories: natural polymers, synthetic polymers, inorganic materials, and metal-containing materials. Hemostatic materials are prepared in various forms for wound care applications based on the active ingredients used. These materials include nanofibers, gels, sponges, and nanoparticles. Hemostatic materials find their applications in the field of wound care, and they are also used for hemostasis during malignant tumor surgery. Prompt and effective hemostasis can reduce the possibility of the spread of tumor cells with blood. This review discusses the outcomes of current research conducted in the field and the problems persisting in the field of developing hemostatic materials. The review also presents a platform for the further development of hemostatic materials. Bleeding caused by trauma or surgery is a serious health problem, and uncontrollable bleeding can result in death. Therefore, developing safe, effective, and convenient hemostatic materials is important. Active hemostatic agents currently used to investigate the field of hemostasis are divided into four broad categories: natural polymers, synthetic polymers, inorganic materials, and metal-containing materials. Hemostatic materials are prepared in various forms for wound care applications based on the active ingredients used. These materials include nanofibers, gels, sponges, and nanoparticles. Hemostatic materials find their applications in the field of wound care, and they are also used for hemostasis during malignant tumor surgery. Prompt and effective hemostasis can reduce the possibility of the spread of tumor cells with blood. This review discusses the outcomes of current research conducted in the field and the problems persisting in the field of developing hemostatic materials. The review also presents a platform for the further development of hemostatic materials.
Key Findings
1
Active hemostatic agents fall into four categories: natural polymers, synthetic polymers, inorganic materials, and metal-containing materials.
2
Current research has produced outcomes and identified persistent problems in hemostatic material development, and the review proposes a platform to guide further development.
3
Hemostatic materials are applied both for general wound care and to achieve hemostasis during malignant tumor surgery to reduce tumor cell dissemination via blood.
4
Hemostatic materials are manufactured in varied forms—nanofibers, gels, sponges, and nanoparticles—tailored for wound care applications.
5
Uncontrolled bleeding from trauma or surgery is a serious health problem that can result in death, motivating development of improved hemostatic materials.
Research Object
Hemostatic materials for medical/wound-care and surgical applications (including natural polymers, synthetic polymers, inorganic and metal-containing materials in forms such as nanofibers, gels, sponges, and nanoparticles)
Research Subject
Design, performance, and clinical applicability of hemostatic materials—safety, effectiveness, convenience, material categories and forms, and their role in achieving prompt hemostasis including use during tumor surgery
Publication Details
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2022-11-29
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