The formation of human populations in South and Central Asia

Формирование человеческих популяций в Южной и Центральной Азии
Jonas Oppenheimer, Nick Patterson, Swapan Mallick, Matthias Meyer, Priya Moorjani, А. П. Деревянко, David Reich, Carles Lalueza‐Fox, Davide Pettener, Mark Lipson, Nadin Rohland, Ron Pinhasi, Kubatbek Tabaldiev, Andrey Epimakhov, Pavel Kuznetsov, David W. Anthony, Nathan Nakatsuka, Iosif Lazaridis, Matthew Ferry, Éadaoin Harney, Megan Michel, Kristin Stewardson, Brendan J. Culleton, Thomas K. Harper, Douglas J. Kennett, Michael D. Frachetti, Mateja Hajdinjak, Kendra Sirak, Viviane Slon, Kumarasamy Thangaraj, Muhammad Zahir, Richard Potts, Nicole Boivin, Vagheesh M. Narasimhan, Dorian Q. Fuller, Andrey Gromov, Aleksandr Khokhlov, Vyacheslav Moiseyev, Katerina Douka, Sergey Slepchenko, Dmitry Razhev, Oleg Dmitrievich Mochalov, Daniel Fernandes, Mario Novak, Maria Teschler‐Nicola, Еgor Kitov, Donata Luiselli, Deborah C. Merrett, Beatriz Gamarra, Janet Monge, Christopher Meiklejohn, Rebecca Bernardos, Íñigo Olalde, Alexander M. Kim, Luca M. Olivieri, Alfredo Coppa, Massimo Vidale, J. P. Mallory, Nicole Adamski, Neel Alex, Nasreen Broomandkhoshbacht, Francesca Candilio, Kimberly Callan, Olivia Cheronet, Suzanne Freilich, Daniel Gaudio, Denise Keating, Ann Marie Lawson, Matthew Mah, Kirsten Mandl, Niraj Rai, Fatma Zalzala, Zhao Zhang, Gaziz Akhatov, A.N. Bagashev, Alessandra Bagnera, Bauryzhan Baitanayev, Julio Bendezú-Sarmiento, Arman A. Bissembaev, Gian Luca Bonora, Temirlan Chargynov, Т. А. Чикишева, Petr K. Dashkovskiy, Miroslav Dobeš, Надежда Дубова, Meiram N. Duisengali, D.N. Enshin, Alexey V. Fribus, Alexander Goryachev, С.П. Грушин, Bryan Hanks, Margaret A. Judd, Erlan Kazizov, Aleksander P. Krygin, Elena Kupriyanova, Farhod Maksudov, Aslan M. Mamedov, Talgat B. Mamirov, Roberto Micheli, Samariddin Mustafokulov, Ayushi Nayak, Marina P. Rykun, Stefania Sarno, Tatyana M. Savenkova, Kulyan Sikhymbaeva, Oroz A. Soltobaev, N. Stepanova, Svetlana V Svyatko, А. Тишкин, В. В. Ткачев, Sergey Vasilyev, Dmitriy Voyakin, Petr Velemínský, А. В. Зубова, Antonina Yermolayeva, Valery S. Zubkov, Vasant Shinde
2019-09-05

Indus Valley Civilization admixtureIranian and Southeast Asian hunter-gatherer ancestry gradientSouth Asian population formationSteppe pastoralist ancestry (Bronze Age)ancient DNA sequencing
By sequencing 523 ancient humans, we show that the primary source of ancestry in modern South Asians is a prehistoric genetic gradient between people related to early hunter-gatherers of Iran and Southeast Asia. After the Indus Valley Civilization's decline, its people mixed with individuals in the southeast to form one of the two main ancestral populations of South Asia, whose direct descendants live in southern India. Simultaneously, they mixed with descendants of Steppe pastoralists who, starting around 4000 years ago, spread via Central Asia to form the other main ancestral population. The Steppe ancestry in South Asia has the same profile as that in Bronze Age Eastern Europe, tracking a movement of people that affected both regions and that likely spread the distinctive features shared between Indo-Iranian and Balto-Slavic languages.
1
After the Indus Valley Civilization's decline, its people mixed with southeastern individuals to form one of the two main ancestral populations of South Asia, with direct descendants in southern India.
2
Sequencing of 523 ancient humans reveals modern South Asians primarily derive from a prehistoric genetic gradient between populations related to Iranian hunter-gatherers and Southeast Asian groups.
3
Simultaneously, Indus-related populations mixed with descendants of Steppe pastoralists who spread via Central Asia starting around 4000 years ago, forming the other main ancestral South Asian population.
4
Steppe-related ancestry in South Asia matches the profile of Bronze Age Eastern European Steppe ancestry, indicating a linked movement of people affecting both regions.
5
The spread of Steppe ancestry likely contributed to shared features between Indo-Iranian and Balto-Slavic languages through this prehistoric migration.

Ancient and modern human populations of South and Central Asia (including sequenced 523 ancient humans)

Formation and admixture history of South Asian ancestry, specifically the prehistoric gradient between Iran-related and Southeast Asian-related groups, post-Indus Valley mixing forming a southern-Indian-descendant ancestral population, and incoming Steppe pastoralist admixture spreading via Central Asia about 4000 years ago

Publication Details
Publication Date
2019-09-05
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Authors
Jonas Oppenheimer
Nick Patterson
Swapan Mallick
Matthias Meyer
Priya Moorjani
А. П. Деревянко
David Reich
Carles Lalueza‐Fox
Davide Pettener
Mark Lipson
Nadin Rohland
Ron Pinhasi
Kubatbek Tabaldiev
Andrey Epimakhov
Pavel Kuznetsov
David W. Anthony
Nathan Nakatsuka
Iosif Lazaridis
Matthew Ferry
Éadaoin Harney
Megan Michel
Kristin Stewardson
Brendan J. Culleton
Thomas K. Harper
Douglas J. Kennett
Michael D. Frachetti
Mateja Hajdinjak
Kendra Sirak
Viviane Slon
Kumarasamy Thangaraj
Muhammad Zahir
Richard Potts
Nicole Boivin
Vagheesh M. Narasimhan
Dorian Q. Fuller
Andrey Gromov
Aleksandr Khokhlov
Vyacheslav Moiseyev
Katerina Douka
Sergey Slepchenko
Dmitry Razhev
Oleg Dmitrievich Mochalov
Daniel Fernandes
Mario Novak
Maria Teschler‐Nicola
Еgor Kitov
Donata Luiselli
Deborah C. Merrett
Beatriz Gamarra
Janet Monge
Christopher Meiklejohn
Rebecca Bernardos
Íñigo Olalde
Alexander M. Kim
Luca M. Olivieri
Alfredo Coppa
Massimo Vidale
J. P. Mallory
Nicole Adamski
Neel Alex
Nasreen Broomandkhoshbacht
Francesca Candilio
Kimberly Callan
Olivia Cheronet
Suzanne Freilich
Daniel Gaudio
Denise Keating
Ann Marie Lawson
Matthew Mah
Kirsten Mandl
Niraj Rai
Fatma Zalzala
Zhao Zhang
Gaziz Akhatov
A.N. Bagashev
Alessandra Bagnera
Bauryzhan Baitanayev
Julio Bendezú-Sarmiento
Arman A. Bissembaev
Gian Luca Bonora
Temirlan Chargynov
Т. А. Чикишева
Petr K. Dashkovskiy
Miroslav Dobeš
Надежда Дубова
Meiram N. Duisengali
D.N. Enshin
Alexey V. Fribus
Alexander Goryachev
С.П. Грушин
Bryan Hanks
Margaret A. Judd
Erlan Kazizov
Aleksander P. Krygin
Elena Kupriyanova
Farhod Maksudov
Aslan M. Mamedov
Talgat B. Mamirov
Roberto Micheli
Samariddin Mustafokulov
Ayushi Nayak
Marina P. Rykun
Stefania Sarno
Tatyana M. Savenkova
Kulyan Sikhymbaeva
Oroz A. Soltobaev
N. Stepanova
Svetlana V Svyatko
А. Тишкин
В. В. Ткачев
Sergey Vasilyev
Dmitriy Voyakin
Petr Velemínský
А. В. Зубова
Antonina Yermolayeva
Valery S. Zubkov
Vasant Shinde
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