Enantioselective synthesis of 2-amino-4<i>H</i>-chromene derivatives with antifungal activities on phytopathogenic fungi
Энантиоселективный синтез производных 2-амино-4H-хромена с противогрибковой активностью в отношении фитопатогенных грибов
2024-01-01
SCID: 54.1/mmhdjuv2
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2-(1-hydroxyallyl)phenols2-amino-4H-chromene derivativesIr-catalyzed reactionantifungal activity against phytopathogenic fungienantioselective cascade allylation/cyclization
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Abstract (AI)
An Ir-catalyzed enantioselective cascade allylation/cyclization reaction of 2-(1-hydroxyallyl)phenols was developed, affording antifungal 2-amino-4 H -chromene derivatives with good to excellent enantioselectivities.
Key Findings
1
An Ir-catalyzed enantioselective cascade allylation/cyclization of 2-(1-hydroxyallyl)phenols was developed.
2
The reaction affords 2-amino-4H-chromene derivatives that possess antifungal activity against phytopathogenic fungi.
3
The synthesized 2-amino-4H-chromene products are obtained with good to excellent enantioselectivities.
Research Object
2-amino-4H-chromene derivatives synthesized via an Ir-catalyzed enantioselective cascade allylation/cyclization of 2-(1-hydroxyallyl)phenols
Research Subject
Enantioselective synthesis (enantioselectivity and reaction efficiency) of these 2-amino-4H-chromene derivatives and their antifungal activity against phytopathogenic fungi
Publication Details
Publication Date
2024-01-01
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