Polymer gel dosimetry

Полимерная гелевая дозиметрия
Mark Oldham, Simon Doran, Clive Baldock, Yves De Deene, G Ibbott, Andrew Jirasek, Martin Lepage, Kimberley B. McAuley, L J Schreiner
2010-02-11

intensity-modulated radiation therapymagnetic resonance imagingpolymer gel dosimetrystereotactic radiosurgerythree-dimensional radiation dosimetry
Polymer gel dosimeters are fabricated from radiation sensitive chemicals which, upon irradiation, polymerize as a function of the absorbed radiation dose. These gel dosimeters, with the capacity to uniquely record the radiation dose distribution in three-dimensions (3D), have specific advantages when compared to one-dimensional dosimeters, such as ion chambers, and two-dimensional dosimeters, such as film. These advantages are particularly significant in dosimetry situations where steep dose gradients exist such as in intensity-modulated radiation therapy (IMRT) and stereotactic radiosurgery. Polymer gel dosimeters also have specific advantages for brachytherapy dosimetry. Potential dosimetry applications include those for low-energy x-rays, high-linear energy transfer (LET) and proton therapy, radionuclide and boron capture neutron therapy dosimetries. These 3D dosimeters are radiologically soft-tissue equivalent with properties that may be modified depending on the application. The 3D radiation dose distribution in polymer gel dosimeters may be imaged using magnetic resonance imaging (MRI), optical-computerized tomography (optical-CT), x-ray CT or ultrasound. The fundamental science underpinning polymer gel dosimetry is reviewed along with the various evaluation techniques. Clinical dosimetry applications of polymer gel dosimetry are also presented.
1
Polymer gel dosimeters polymerize in proportion to absorbed radiation dose, enabling recording of three-dimensional dose distributions.
2
Polymer gel dosimetry provides specific benefits for brachytherapy and may support dosimetry for low-energy x-rays, high-LET and proton therapy, radionuclide therapy, and boron capture neutron therapy.
3
Recorded dose distributions can be evaluated using MRI, optical CT, x-ray CT, or ultrasound; the review covers underlying science, evaluation methods, and clinical applications.
4
Their 3D measurement capability offers advantages over one-dimensional ion chambers and two-dimensional film, especially in steep-gradient treatments such as IMRT and stereotactic radiosurgery.
5
These dosimeters are radiologically soft-tissue equivalent, with properties adjustable for different applications.

Polymer gel dosimeters

their radiation-induced polymerization, three-dimensional radiation-dose recording, imaging/evaluation, and clinical dosimetry applications

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Publication Date
2010-02-11
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Authors
Mark Oldham
Simon Doran
Clive Baldock
Yves De Deene
G Ibbott
Andrew Jirasek
Martin Lepage
Kimberley B. McAuley
L J Schreiner
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