intensity-modulated radiation therapymagnetic resonance imagingpolymer gel dosimetrystereotactic radiosurgerythree-dimensional radiation dosimetry
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Abstract (AI)
Polymer gel dosimeters are fabricated from radiation sensitive chemicals which, upon irradiation, polymerize as a function of the absorbed radiation dose. These gel dosimeters, with the capacity to uniquely record the radiation dose distribution in three-dimensions (3D), have specific advantages when compared to one-dimensional dosimeters, such as ion chambers, and two-dimensional dosimeters, such as film. These advantages are particularly significant in dosimetry situations where steep dose gradients exist such as in intensity-modulated radiation therapy (IMRT) and stereotactic radiosurgery. Polymer gel dosimeters also have specific advantages for brachytherapy dosimetry. Potential dosimetry applications include those for low-energy x-rays, high-linear energy transfer (LET) and proton therapy, radionuclide and boron capture neutron therapy dosimetries. These 3D dosimeters are radiologically soft-tissue equivalent with properties that may be modified depending on the application. The 3D radiation dose distribution in polymer gel dosimeters may be imaged using magnetic resonance imaging (MRI), optical-computerized tomography (optical-CT), x-ray CT or ultrasound. The fundamental science underpinning polymer gel dosimetry is reviewed along with the various evaluation techniques. Clinical dosimetry applications of polymer gel dosimetry are also presented.
Key Findings
1
Polymer gel dosimeters polymerize in proportion to absorbed radiation dose, enabling recording of three-dimensional dose distributions.
2
Polymer gel dosimetry provides specific benefits for brachytherapy and may support dosimetry for low-energy x-rays, high-LET and proton therapy, radionuclide therapy, and boron capture neutron therapy.
3
Recorded dose distributions can be evaluated using MRI, optical CT, x-ray CT, or ultrasound; the review covers underlying science, evaluation methods, and clinical applications.
4
Their 3D measurement capability offers advantages over one-dimensional ion chambers and two-dimensional film, especially in steep-gradient treatments such as IMRT and stereotactic radiosurgery.
5
These dosimeters are radiologically soft-tissue equivalent, with properties adjustable for different applications.
Research Object
Polymer gel dosimeters
Research Subject
their radiation-induced polymerization, three-dimensional radiation-dose recording, imaging/evaluation, and clinical dosimetry applications
Publication Details
Publication Date
2010-02-11
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