Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

Enrichr: комплексный веб-сервер для анализа обогащения наборов генов — обновление 2016 года
Simon Koplev, Maxim V. Kuleshov, Matthew R. Jones, Andrew D. Rouillard, Nicolas Fernandez, Qiaonan Duan, Zichen Wang, Sherry L. Jenkins, Kathleen M. Jagodnik, Alexander Lachmann, Michael G. McDermott, Caroline D. Monteiro, Gregory W. Gundersen, Avi Ma’ayan, Matthew R. Jones
2016-05-03

BED file uploadEnrichrclustergram visualizationgene set enrichment analysisgene set libraries
Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide experiments. Here we present a significant update to one of the tools in this domain called Enrichr. Enrichr currently contains a large collection of diverse gene set libraries available for analysis and download. In total, Enrichr currently contains 180 184 annotated gene sets from 102 gene set libraries. New features have been added to Enrichr including the ability to submit fuzzy sets, upload BED files, improved application programming interface and visualization of the results as clustergrams. Overall, Enrichr is a comprehensive resource for curated gene sets and a search engine that accumulates biological knowledge for further biological discoveries. Enrichr is freely available at: http://amp.pharm.mssm.edu/Enrichr.
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Enrichr added support for submitting fuzzy gene sets and uploading BED files for enrichment analysis.
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Enrichr functions as a freely available resource and search engine for curated gene sets and accumulated biological knowledge.
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The 2016 Enrichr update provides access to 180,184 annotated gene sets across 102 diverse gene set libraries.
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The updated platform includes an improved application programming interface and clustergram-based visualization of enrichment results.

Enrichr web server and its curated gene set libraries

gene set enrichment analysis capabilities, including library coverage, fuzzy-set and BED-file submission, API functionality, and result visualization

Publication Details
Publication Date
2016-05-03
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ISSN
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Authors
Simon Koplev
Maxim V. Kuleshov
Matthew R. Jones
Andrew D. Rouillard
Nicolas Fernandez
Qiaonan Duan
Zichen Wang
Sherry L. Jenkins
Kathleen M. Jagodnik
Alexander Lachmann
Michael G. McDermott
Caroline D. Monteiro
Gregory W. Gundersen
Avi Ma’ayan
Matthew R. Jones
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