Assessing thromboelastometry, coagulation and fluid resuscitation strategies in postpartum haemorrhage

Оценка тромбоэластометрии, коагуляции и стратегий инфузионной терапии при послеродовом кровотечении
Natascha Mmapula de Lange
2026-01-01

ROTEM thromboelastometrycoagulation testingpostpartum haemorrhagepregnancy hypercoagulabilityrestrictive fluid resuscitation
This thesis determined reference values for ROTEM thromboelastometry during labour. The hypercoaguable state in pregnancy was confirmed, as was the correlation between some ROTEM parameters and conventional laboratory tests. The chance of abnormal coagulation values is low. In the second part the thesis investigated the effect of restrictive fluid resuscitation in women with mild postpartum haemorrhage. Restrictive fluid resuscitation is not inferior to standard therapy.
1
Abnormal coagulation values were uncommon during labour.
2
Reference values for ROTEM thromboelastometry during labour were established.
3
Restrictive fluid resuscitation was not inferior to standard therapy in women with mild postpartum haemorrhage.
4
Some ROTEM parameters correlated with conventional laboratory coagulation tests.
5
The hypercoagulable state of pregnancy was confirmed using ROTEM assessments.

Labouring women and women with mild postpartum haemorrhage

ROTEM thromboelastometry reference values, coagulation characteristics, and the comparative effect of restrictive versus standard fluid resuscitation

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2026-01-01
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Natascha Mmapula de Lange
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