Efficacy and Tolerability of Overnight Bladder Drainage After Posterior Urethral Valve Ablation on Upper and Lower Urinary Tracts: A Randomized Controlled Trial

PURPOSE: The purpose of this study was to assess the effect of overnight bladder drainage (OBD) on upper and lower urinary tracts of boys after endoscopic valve ablation (EVA). MATERIALS AND METHODS: Tc-dimercaptosuccinic acid scan, febrile urinary tract infections (UTIs), and tolerability to OBD. RESULTS: A total of 99 patients, 47 patients with OBD and 52 patients with no OBD, were included between September 2021 and August 2023. OBD showed significant improvement in HN, VUR, renal parenchymal area, bladder capacity, outline, detrusor overactivity, compliance, daytime continence, and nocturnal polyuria. However, no significant difference was noted regarding bladder wall thickness, postvoid residual urine, bladder sensation, detrusor leak point pressure, maximum flow rate, flow curve morphology, renal function, renal scarring, and febrile UTIs. Tolerability to OBD was reported in 87%. CONCLUSIONS: OBD, apart from patients' tolerability, improves HN, VUR, renal parenchymal growth, abnormal bladder morphology and dynamics, daytime continence, and nocturnal polyuria that persist after EVA with no consequent renal function affection or febrile UTIs.