Association of cognitive impairment and arterial hypertension

Связь когнитивных нарушений и артериальной гипертензии
О. Yu. Isaykina, K. A. Vekhova, G. S. Drobotov, Renat Takhirov, M. A. Isaykina, В. М. Горбунов
2023-12-16

arterial hypertensionarterial stiffnesscognitive functioncognitive impairmentendothelial dysfunction
Impaired cognitive function (CF) is a common manifestation of brain damage as a target organ of arterial hypertension (AH). The presence of hypertension in middle age increases the risk of developing cognitive impairment (CI) and dementia in old age. At the same time, changes in certain indicators characteristic of AH may serve as predictors of CI and dementia in the future. The review presents data on the effects of endothelial dysfunction and increased arterial stiffness on CF. The small number of papers on the effects of hypertension in middle-aged people on the development of CI emphasizes the importance of investigating this topic, as the incidence of CI in young and middle-aged people has increased in recent years.
1
Changes in hypertension-related indicators may help predict future cognitive impairment and dementia.
2
Cognitive impairment is a common manifestation of hypertensive brain target-organ damage.
3
Endothelial dysfunction and increased arterial stiffness are implicated in adverse effects of hypertension on cognitive function.
4
Hypertension during middle age is associated with increased risk of cognitive impairment and dementia in later life.
5
Limited evidence on hypertension and cognitive impairment in middle-aged adults highlights the need for further research, particularly amid rising incidence in younger populations.

arterial hypertension in middle-aged people

the association of endothelial dysfunction and increased arterial stiffness with cognitive impairment and cognitive function decline

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Publication Date
2023-12-16
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Authors
О. Yu. Isaykina
K. A. Vekhova
G. S. Drobotov
Renat Takhirov
M. A. Isaykina
В. М. Горбунов
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