Metabolic consequences of cystinuria
Метаболические последствия цистинурии
2019-06-20
SCID: 54.1/qt9x6v6a
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animal modelchronic kidney diseasecystinuriadietary effectsoxidative stress injuryreduced glutathione
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Abstract (AI)
Our results suggest that that diet can affect the development and progression of chronic kidney disease in an animal model of cystinuria, which may have important implications for patients with this disease. Additionally, reduced glutathione may predispose those with cystinuria to injury caused by oxidative stress. Word count: 327.
Key Findings
1
Diet influences development and progression of chronic kidney disease in an animal model of cystinuria
2
Findings in the animal model have important implications for management of patients with cystinuria
3
Reduced glutathione may predispose individuals with cystinuria to oxidative stress–induced injury
Research Object
Animal model of cystinuria
Research Subject
Metabolic consequences including diet-modulated progression of chronic kidney disease and reduced glutathione–linked susceptibility to oxidative stress injury in cystinuria
Publication Details
Publication Date
2019-06-20
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