Anton’s syndrome: a rare and unusual form of blindness

Синдром Антона: редкая и необычная форма слепоты
Faisal Bashir Chaudhry, Samavia Raza, Usman Ahmad
2019-12-01

Anton syndromebilateral occipital lobe damagecortical blindnessposterior reversible encephalopathy syndromevisual anosognosia
Anton syndrome is characterised by visual anosognosia. It results from damage to both occipital lobes, while the anterior visual pathways remain intact. We describe four cases of Anton's syndrome. First case is that of a 73-year-old woman, who presented with two separate events of intraparenchymal brain haemorrhage, 4 years apart. Her first stroke affected the left and second affected the right occipital lobe. Bilateral occipital lobe damage resulted in cortical blindness. Second case is an 88-year-old man, who suffered from two ischaemic strokes, 2 days apart. Each stroke involved one posterior cerebral artery. This resulted in bilateral occipital and temporal lobe infarcts. Third case is a 64-year-old woman with chronic renal failure, who suffered bilateral occipital lobe infarction after haemodialysis, due to posterior reversible encephalopathy syndrome. Last case is that of an 80-year-old woman who suffered a basilar artery stroke, resulting in bilateral thalamic, temporal and occipital lobe infarction.
1
A basilar artery stroke caused bilateral thalamic, temporal, and occipital infarctions associated with Anton syndrome.
2
Anton syndrome is visual anosognosia caused by bilateral occipital damage with intact anterior visual pathways, producing cortical blindness.
3
Four cases demonstrate that Anton syndrome can follow bilateral occipital injury from sequential hemorrhages, bilateral posterior cerebral artery ischemic strokes, or other vascular events.
4
One patient developed bilateral occipital infarction after hemodialysis-associated posterior reversible encephalopathy syndrome in the setting of chronic renal failure.
5
The cases highlight diverse cerebrovascular mechanisms leading to bilateral posterior brain injury and cortical blindness with unawareness of visual loss.

Anton syndrome (visual anosognosia) associated with bilateral occipital brain damage in four clinical cases

The clinical manifestations and lesion patterns underlying cortical blindness and visual anosognosia

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2019-12-01
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Faisal Bashir Chaudhry
Samavia Raza
Usman Ahmad
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