An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy
О роли нанопереносчиков фотосенсибилизаторов в фотодинамической терапии
2018-01-01
SCID: 54.1/s5kzyrj5
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Cancer treatmentPhotodynamic therapyPhotosensitizer nanocarriersReactive oxygen speciesTetrapyrrolic photosensitizers
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Abstract (AI)
Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment.
Key Findings
1
PDT outcomes depend substantially on efficient photosensitizer delivery and the ability to target tumor tissues.
2
Photodynamic therapy destroys tumor cells through reactive oxygen species generated when photosensitizers are activated by visible or near-infrared light.
3
Photosensitizer nanocarriers are highlighted as delivery platforms with potential to enhance PDT performance.
4
The review examines how drug-delivery systems can improve the therapeutic efficiency of tetrapyrrolic photosensitizers.
Research Object
drug delivery systems (photosensitizer nanocarriers) for tetrapyrrolic photosensitizers in cancer photodynamic therapy
Research Subject
the role of nanocarriers in improving tetrapyrrolic photosensitizer delivery, targeting ability, and photodynamic therapy efficiency
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2018-01-01
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