A dynamic mucin mRNA signature associates with COVID-19 disease presentation and severity

Haug, S; Li, Y; Cheng, Y; Consolato, F; Schiano, G; Chong, MR; Pietzner, M; Nguyen, NQH; Scherer, N; Biggs, ML; Kleber, ME; Goecmen, B; Pigeyre, M; Sekula, P; Steinbrenner, I; Schlosser, P; Joseph, CB; Brody, JA; Grams, ME; Hayward, C; Schultheiss, UT; Kraemer, BK; Kronenberg, F; Peters, A; Seissler, J; Steubl, D; Then, C; Wuttke, M; Maerz, W; Eckardt, K-U; Gieger, C; Boerwinkle, E; Psaty, BM; Coresh, J; Oefner, PJ; Pare, G; Langenberg, C; Scherberich, JE; Yu, B; Akilesh, S; Devuyst, O; Rampoldi, L; Koettgen, A

doi:10.1172/jci

A dynamic mucin mRNA signature associates with COVID-19 disease presentation and severity

Динамическая сигнатура мРНК муцинов связана с клиническими проявлениями и тяжестью течения COVID-19

Haug, S, Li, Y, Cheng, Y, Consolato, F, Schiano, G, Chong, MR, Pietzner, M, Nguyen, NQH, Scherer, N, Biggs, ML, Kleber, ME, Goecmen, B, Pigeyre, M, Sekula, P, Steinbrenner, I, Schlosser, P, Joseph, CB, Brody, JA, Grams, ME, Hayward, C, Schultheiss, UT, Kraemer, BK, Kronenberg, F, Peters, A, Seissler, J, Steubl, D, Then, C, Wuttke, M, Maerz, W, Eckardt, K-U, Gieger, C, Boerwinkle, E, Psaty, BM, Coresh, J, Oefner, PJ, Pare, G, Langenberg, C, Scherberich, JE, Yu, B, Akilesh, S, Devuyst, O, Rampoldi, L, Koettgen, A

2021-08-10

SCID: 54.1/tb4jwqgj Discuss with AI

COVID-19 disease presentationCOVID-19 disease severitymucin mRNA signature

Abstract (AI)

Institute of Virology, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Medical Faculty. Düsseldorf, Germany.

Key Findings

Mucin mRNA expression is associated with COVID-19 severity.

The mucin mRNA signature varies dynamically across COVID-19 disease presentations.

The study concerns a dynamic mucin mRNA signature associated with COVID-19 disease presentation and severity.

Research Object

Mucin mRNA expression in patients with COVID-19

Research Subject

Dynamic mucin mRNA signature associated with COVID-19 disease presentation and severity

Publication Details

DOI

10.1172/jci

Publication Date

2021-08-10

Journal

Publisher

ISSN

Cited by

Open access PDF

https://hal.science/hal-04961086/document

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Author Information

Authors

Haug, S

Li, Y

Cheng, Y

Consolato, F

Schiano, G

Chong, MR

Pietzner, M

Nguyen, NQH

Scherer, N

Biggs, ML

Kleber, ME

Goecmen, B

Pigeyre, M

Sekula, P

Steinbrenner, I

Schlosser, P

Joseph, CB

Brody, JA

Grams, ME

Hayward, C

Schultheiss, UT

Kraemer, BK

Kronenberg, F

Peters, A

Seissler, J

Steubl, D

Then, C

Wuttke, M

Maerz, W

Eckardt, K-U

Gieger, C

Boerwinkle, E

Psaty, BM

Coresh, J

Oefner, PJ

Pare, G

Langenberg, C

Scherberich, JE

Yu, B

Akilesh, S

Devuyst, O

Rampoldi, L

Koettgen, A

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