АТЕРОСКЛЕРОЗ (АДАБИЁТЛАР ШАРҲИ)

Атеросклероз (обзор литературы)
Махмудов, Равшан Барраевич, Шаропова, Гулнигор Кунтуғмиш қизи
2025-12-09

atherosclerosisendothelial dysfunctioninflammationoxidized LDLplaque stabilitypreventionstatins
Резюме. Ушбу мақолада атеросклероз касаллиги бўйича замонавий адабиётлар таҳлили келтирилган. Эндотелий дисфункцияси, липид алмашинувининг бузилиши, яллиғланиш механизмлари ва атеросклеротик пилакча ривожланишининг молекуляр асослари ёритилган. Шунингдек, диагностика усуллари, хавф омиллари ва замонавий даволаш стратегияларининг самарадорлиги ҳақида илмий манбалар асосида хулосалар берилган. Таҳлиллар атеросклерозни барвақт аниқлаш ва профилактика қилишнинг долзарблигини янада тасдиқлайди. Калит сўзлар: атеросклероз, эндотелий дисфункцияси, оксидланган LDL, яллиғланиш, пилакча барқарорлиги, статинлар, профилактика
1
Analyses emphasize the importance of early detection and prevention of atherosclerosis.
2
Diagnostics, risk factors, and effectiveness of modern treatment strategies (including statins) are evaluated based on scientific sources.
3
Oxidized LDL and endothelial dysfunction are highlighted as central mechanisms driving atherogenesis.
4
Plaque stability and inflammatory mechanisms are discussed as key determinants of disease progression and therapeutic targets.
5
Review summarizes molecular bases of atherosclerotic plaque development, including endothelial dysfunction, disturbed lipid metabolism, and inflammation.

Atherosclerosis disease (atherosclerotic plaques and related vascular processes)

Molecular mechanisms, pathophysiology and clinical aspects including endothelial dysfunction, lipid metabolism disturbance (oxidized LDL), inflammation, plaque development and stability, risk factors, diagnostic methods and treatment/prevention strategies

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2025-12-09
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Махмудов, Равшан Барраевич
Шаропова, Гулнигор Кунтуғмиш қизи
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