Revolutionizing Drug Delivery: The Impact of Advanced Materials Science and Technology on Precision Medicine
Революция в доставке лекарственных средств: влияние передовых достижений материаловедения и технологий на прецизионную медицину
2025-03-15
SCID: 54.1/ukeztfs6
Discuss with AI
bioresponsive polymersmicrofluidicsnanocarrierspersonalized medicineprecision drug delivery
Figures from the paper
Abstract (AI)
Recent progress in material science has led to the development of new drug delivery systems that go beyond the conventional approaches and offer greater accuracy and convenience in the application of therapeutic agents. This review discusses the evolutionary role of nanocarriers, hydrogels, and bioresponsive polymers that offer enhanced drug release, target accuracy, and bioavailability. Oncology, chronic disease management, and vaccine delivery are some of the applications explored in this paper to show how these materials improve the therapeutic results, counteract multidrug resistance, and allow for sustained and localized treatments. The review also discusses the translational barriers of bringing advanced materials into the clinical setting, which include issues of biocompatibility, scalability, and regulatory approval. Methods to overcome these challenges include surface modifications to reduce immunogenicity, scalable production methods such as microfluidics, and the harmonization of regulatory systems. In addition, the convergence of artificial intelligence (AI) and machine learning (ML) is opening new frontiers in material science and personalized medicine. These technologies allow for predictive modeling and real-time adjustments to optimize drug delivery to the needs of individual patients. The use of advanced materials can also be applied to rare and underserved diseases; thus, new strategies in gene therapy, orphan drugs development, and global vaccine distribution may offer new hopes for millions of patients.
Key Findings
1
Advanced drug-delivery materials, including nanocarriers, hydrogels, and bioresponsive polymers, improve release control, targeting accuracy, and drug bioavailability.
2
Artificial intelligence and machine learning enable predictive modeling and real-time personalization of drug delivery, including applications for rare diseases, gene therapy, orphan drugs, and global vaccine distribution.
3
Clinical translation remains limited by biocompatibility, manufacturing scalability, and regulatory-approval challenges.
4
Surface modification, scalable microfluidic production, and regulatory harmonization are identified as strategies to address translational barriers.
5
These materials support oncology, chronic-disease management, and vaccine delivery through sustained and localized treatment while potentially counteracting multidrug resistance.
Research Object
advanced-material drug delivery systems, including nanocarriers, hydrogels, and bioresponsive polymers
Research Subject
their precision, target accuracy, drug-release control, bioavailability, therapeutic effectiveness, and clinical translation barriers
Publication Details
Publication Date
2025-03-15
Journal
Publisher
ISSN
Cited by
88
Open access PDF
Access Type
Author Information
Download PDF
Subscribe to digest