Is Vesicostomy Still a Contemporary Method of Managing Posterior Urethral Valves?
Является ли везикостомия по-прежнему современным методом лечения задних клапанов уретры?
2022-01-21
SCID: 54.1/vp8jps67
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bladder and renal functionposterior urethral valvessecondary vesicostomyurodynamic measurementsvesicoureteral reflux
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Abstract (AI)
In boys with posterior urethral valves (PUVs) the main treatment aim is to preserve long-term bladder and renal function. To determine the effectiveness of secondary vesicostomy in boys with PUVs, the medical records of 21 patients with PUV (2010–2019), divided into two groups (group I: valve ablation; group II: secondary vesicostomy), were reviewed regarding the course of serum creatinine, renal ultrasound, voiding cystourethrogram, urodynamics, postoperative complications, need of further surgery, and long-term solution. The median age of all patients at first follow-up was 11 (9–13) months and at last follow-up 64.5 (39.5–102.5) months. Despite a significant difference of the SWDR score (shape, wall, reflux, and diverticula) (p = 0.014), both groups showed no significant differences preoperatively. Postoperatively, serum creatinine (p = 0.024), grade of vesicoureteral reflux (p = 0.003), side of upper tract dilatation (p = 0.006), side of megaureter (p = 0.004), and SWDR score (p = 0.002) were significantly decreased in group II. Postoperative urodynamic measurements showed comparable results in both groups. Stoma complications were found in three (20%) patients (group II). Eight (53.3%) patients already received a closure of the vesicostomy. Seven out of eight (87.5%) patients were able to micturate spontaneously. Vesicostomy remains a reliable treatment option for boys with PUV to improve bladder function and avoid further damage to the urinary tract.
Key Findings
1
Postoperative urodynamic measurements were comparable between boys treated with primary valve ablation and those receiving secondary vesicostomy.
2
Secondary vesicostomy remains a reliable option for improving bladder function and preventing further urinary-tract damage in boys with posterior urethral valves.
3
Secondary vesicostomy significantly improved serum creatinine, vesicoureteral reflux grade, upper-tract dilatation, megaureter, and SWDR scores in boys with posterior urethral valves.
4
Stoma complications occurred in 20% of patients who underwent secondary vesicostomy.
5
Vesicostomy closure was performed in 53.3% of patients, and 87.5% of those subsequently voided spontaneously.
Research Object
Boys with posterior urethral valves managed by valve ablation or secondary vesicostomy
Research Subject
The effectiveness of secondary vesicostomy in preserving bladder and renal function and preventing further urinary-tract damage
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2022-01-21
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