The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions
Расширение имиджинга в UK Biobank для 100 000 участников: обоснование, сбор данных, управление и перспективы
2020-05-26
SCID: 54.1/vygcxhg4
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UK Biobank imaging enhancementbrain, cardiac and abdominal magnetic resonance imaging (MRI)carotid ultrasounddual-energy X-ray absorptiometry (DXA)multi-modal imaging
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Abstract (AI)
UK Biobank is a population-based cohort of half a million participants aged 40-69 years recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi-modal imaging study, with the aim of re-inviting 100,000 participants to undergo brain, cardiac and abdominal magnetic resonance imaging, dual-energy X-ray absorptiometry and carotid ultrasound. The combination of large-scale multi-modal imaging with extensive phenotypic and genetic data offers an unprecedented resource for scientists to conduct health-related research. This article provides an in-depth overview of the imaging enhancement, including the data collected, how it is managed and processed, and future directions.
Key Findings
1
Imaging modalities collected include brain, cardiac and abdominal MRI, dual-energy X-ray absorptiometry, and carotid ultrasound.
2
The imaging data are combined with extensive phenotypic and genetic data to create an unprecedented resource for health-related research.
3
The paper describes in-depth how the imaging data are collected, managed, and processed and outlines future directions for the resource.
4
UK Biobank initiated the world's largest multi-modal imaging study in 2014 to re-invite 100,000 participants for imaging.
Research Object
UK Biobank imaging enhancement of 100,000 participants (multi-modal imaging dataset including brain, cardiac and abdominal MRI, DXA, and carotid ultrasound)
Research Subject
Rationale, data collection, management, processing and future directions of the large-scale multi-modal imaging resource linked to extensive phenotypic and genetic data
Publication Details
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2020-05-26
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