Nanoplastics and Microplastics May Be Damaging Our Livers

Нано- и микропластики могут повреждать нашу печень
Jianli Yin, Ye Ju, Honghao Qian, Jia Wang, Xiaohan Miao, Ying Zhu, Liting Zhou, Ye Lin
2022-10-04

hepatic metabolismliver toxicitymicroplasticsnanoplasticssystematic review
Plastics in the environment can be degraded and even broken into pieces under the action of natural factors, and the degraded products with a particle size of less than 5 mm are called microplastics (MPs). MPs exist in a variety of environmental media that come into contact with the human body. It can enter the body through environmental media and food chains. At present, there are many studies investigating the damage of MPs to marine organisms and mammals. The liver is the largest metabolizing organ and plays an important role in the metabolism of MPs in the body. However, there is no available systematic review on the toxic effects of MPs on the liver. This paper summarizes the adverse effects and mechanisms of MPs on the liver, by searching the literature and highlighting the studies that have been published to date, and provides a scenario for the liver toxicity caused by MPs.
1
Microplastics are environmental degradation products smaller than 5 mm that can enter the human body through environmental media and food chains.
2
The liver plays an important role in metabolizing microplastics after they enter the body.
3
The paper outlines a scenario describing potential liver toxicity caused by microplastics and nanoplastics.
4
The paper provides a systematic literature-based summary of microplastic adverse effects and toxicity mechanisms in the liver.
5
The review addresses a gap by synthesizing evidence on hepatic toxicity, for which no systematic review was previously available.

Liver exposure to environmental microplastics and nanoplastics

Adverse toxic effects and underlying mechanisms of microplastics and nanoplastics on liver function and metabolism

Publication Details
Publication Date
2022-10-04
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Authors
Jianli Yin
Ye Ju
Honghao Qian
Jia Wang
Xiaohan Miao
Ying Zhu
Liting Zhou
Ye Lin
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