Application of a portable primary standard level graphite calorimeter for absolute dosimetry in a clinical low-energy passively scattered proton beam

Применение портативного графитового калориметра уровня первичного эталона для абсолютной дозиметрии в клиническом низкоэнергетическом пассивно рассеянном пучке протонов
F. Romanò, Hugo Palmans, D R Shipley, Russell Thomas, Andrzej Kacperek, S Duane, Ana Lourenço, N Lee, M Cashmore, G. Bass
2022-09-28

Primary Standard Proton Calorimeter (PSPC)absolute dosimetryionisation chamber calibrationkQ valueslow-energy passively scattered proton beam
Abstract Objective . A calibration service based on a primary standard calorimeter for the direct determination of absorbed dose for proton beams does not exist. A new Code of Practice (CoP) for reference dosimetry of proton beams is being developed by a working party of the UK Institute of Physics and Engineering in Medicine (IPEM), which will recommend that ionisation chambers are calibrated directly in their clinical beams against the proposed Primary Standard Proton Calorimeter (PSPC) developed at the National Physical Laboratory (NPL). The aim of this work is to report on the use of the NPL PSPC to directly calibrate ionisation chambers in a low-energy passively scattered proton beam following recommendations of the upcoming IPEM CoP. Approach . A comparison between the dose derived using the proposed IPEM CoP and the IAEA TRS-398 protocol was performed, and k Q values were determined experimentally for three types of chambers. In total, 9 plane-parallel and 3 cylindrical chambers were calibrated using the two protocols for two separate visits. Main results . The ratio of absorbed dose to water obtained with the PSPC and with ionisation chambers applying TRS-398 varied between 0.98 and 1.00, depending on the chamber type. The new procedure based on the PSPC provides a significant improvement in uncertainty where absorbed dose to water measured with a user chamber is reported with an uncertainty of 0.9% (1 σ ), whereas the TRS-398 protocol reports an uncertainty of 2.0% and 2.3% (1 σ ) for cylindrical and plane-parallel chambers, respectively. The k Q values found agree within uncertainties with those from TRS-398 and Monte Carlo calculations. Significance . The establishment of a primary standard calorimeter for the determination of absorbed dose in proton beams combined with the introduction of the associated calibration service following the IPEM recommendations will reduce the uncertainty and improve consistency in the dose delivered to patients.
1
Absorbed dose to water ratios between PSPC measurements and ionisation chambers applying IAEA TRS-398 ranged from 0.98 to 1.00, depending on chamber type.
2
Calibrations were performed for 9 plane-parallel and 3 cylindrical chambers across two visits, and experimentally determined kQ values agree within uncertainties with TRS-398 and Monte Carlo results.
3
Introducing a primary standard calorimeter and associated calibration service per IPEM recommendations will reduce uncertainty and improve consistency in patient proton dose delivery.
4
The NPL Primary Standard Proton Calorimeter (PSPC) was used to directly calibrate ionisation chambers in a low-energy passively scattered proton beam following IPEM CoP recommendations.
5
The PSPC-based procedure reduces uncertainty: absorbed dose with a user chamber reported with 0.9% (1σ), versus 2.0% (cylindrical) and 2.3% (plane-parallel) using TRS-398.

Portable Primary Standard Proton Calorimeter (PSPC) used to directly calibrate ionisation chambers in a low-energy passively scattered clinical proton beam

Absolute dosimetry: determination of absorbed dose to water and calibration coefficients (kQ) for plane-parallel and cylindrical ionisation chambers using the PSPC versus IAEA TRS-398, including associated measurement uncertainties

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Publication Date
2022-09-28
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Authors
F. Romanò
Hugo Palmans
D R Shipley
Russell Thomas
Andrzej Kacperek
S Duane
Ana Lourenço
N Lee
M Cashmore
G. Bass
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